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SNAP25 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6253219

MBS6253219 is an antibody targeting SNAP25. Also known as SNAP25 (Synaptosomal-associated Protein 25, SNAP-25, bA416N4.2, dJ1068F16.2, FLJ23079, HGNC:11132, Resistance to Inhibitors of Cholinesterase 4 Homolog, RIC4, RIC-4, SEC9, SNP25, Super Protein, SUP)… More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SNAP25, Monoclonal Antibody
Full Product Name
SNAP25 (Synaptosomal-associated Protein 25, SNAP-25, bA416N4.2, dJ1068F16.2, FLJ23079, HGNC:11132, Resistance to Inhibitors of Cholinesterase 4 Homolog, RIC4, RIC-4, SEC9, SNP25, Super Protein, SUP) (MaxLight 405)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H2886
Host
Mouse
Species Reactivity
Hamster, Human, Porcine, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight405.
Purity/Purification
Purified by protein A affinity chromatography from tissue culture supernatant.
Specificity
Recognizes human SNAP-25; an antigen of 26-27kD molecular weight. Will react with SNAP-25 from COS cells, but not with the fusion protein from bacterial systems. Species Crossreactivity: rat, hamster, gerbil and porcine
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Molecular Weight
50,688 Da
Immunogen
Crude human synaptic immunoprecipitate.
Conjugate
MaxLight405

Product Categories/Family for anti-SNAP25 antibody

Applications Tested/Suitable for anti-SNAP25 antibody
FLISA, Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-SNAP25 antibody

IHC staining of human cerebellar neurons usingMBS608924.
Mouse Anti-SNAP25 Monoclonal Antibody – Cat# MBS6253219

Product References and Citations for anti-SNAP25 antibody

1. Honer, W.G., et al., 1994, Hippocampal synaptic pathology in patients with temporal lobe epilepsy. Acta Neuropathol. 87: 202-210. 2. Honer, W.G., et al., 1992, Regional synaptic pathology in Alzheimer's disease. Neurobiol. Aging. 13: 375-382. 3. Honer, W.G., et al., 1993, Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex. Brain Res. 609: 9-20. 4. Honer, W.G., et al., 1992, Characterization of a synaptic antigen of interest in neuropsychiatric illness. Biol. Phychiatry 31: 147-158. 5. Honer, W.G., et al., 1989, Monoclonal antibodies to study the brain in schizophrenia. Brain Res. 500: 379-383. 6. Masliah, E., et al., 1994, Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus. Acta Neuropathol. 87: 135-142. 7. Simpson, I.A., et al., 1994, Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease. Ann Neurol. 35: 546-551. 8. Wakabayashi, K., et al., 1994, Synapse alterations in the hippocampalentorhinal formation in Alzheimer's disease with and without Lewy body disease. Brain Research 667: 24-32. 9. Dickson, D.W., et al., 1994, Hippocampal sclerosis: a common pathological feature of dementia in very old (>80 years of age) humans. Acta Neuropathologica 88: 212-221. 10. Dickson, D.W., et al., 1995, Correlations of synaptic markers with cognitive status in prospectively studied elderly humans. Neurobiol Aging (in press).

Other Notes

Small volumes of anti-SNAP25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SNAP25. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chromogranin-A isoform 1 preproprotein
NCBI Official Synonym Full Names
chromogranin A (parathyroid secretory protein 1)
NCBI Official Symbol
CHGA
NCBI Official Synonym Symbols
CGA
NCBI Protein Information
chromogranin-A; SP-I; betagranin (N-terminal fragment of chromogranin A); catestatin; chromofungin; parathyroid secretory protein 1; pituitary secretory protein I

NCBI Summary for SNAP25

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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