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CD14 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6253425

MBS6253425 is an antibody targeting CD14. Also known as CD14 (CD14 Antigen, Lipopolysaccharide Receptor, LPSR, Monocyte Differentiation Antigen 14, Myeloid Cell Specific Leucine Rich Glycoprotein) (MaxLight 490). Reactive in Bovine, Canine, Feline, Goat,… More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD14, Monoclonal Antibody
Full Product Name
CD14 (CD14 Antigen, Lipopolysaccharide Receptor, LPSR, Monocyte Differentiation Antigen 14, Myeloid Cell Specific Leucine Rich Glycoprotein) (MaxLight 490)
Product Gene Name
anti-CD14 antibody
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
3H501
Host
Mouse
Species Reactivity
Bovine, Canine, Feline, Goat, Human, Monkey, Porcine, Rabbit, Sheep
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight490.
Purity/Purification
Purified by protein A affinity chromatography from tissue culture supernatant.
Specificity
Recognizes human CD14. Species Crossreactivity: canine, goat, feline, rabbit, mink, bovine, porcine, sheep, Cynomolgus monkey and llama.
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Molecular Weight
53kDa
Chromosome Location
Chromosome: 5; NC_000005.9 (140011313..140013286, complement). Location: 5q31.1
OMIM
158120
3D Structure
ModBase 3D Structure for P08571
Conjugate
MaxLight490

Product Categories/Family for anti-CD14 antibody

Antibodies; CD Markers
Applications Tested/Suitable for anti-CD14 antibody
Flow Cytometry (FC/FACS), FLISA, Western Blot (WB)

Product References and Citations for anti-CD14 antibody

1. Yoshino, N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp. Anim. 49 (2): 97-110, 2. Soell, M et al. (1995) Activation of human monocytes by streptococcal rhamnose glucose polymers is mediated by CD14 antigen, and mannan binding protein inhibits TNF-alpha release. J. Immunol. 154: 851-860, 3. Gupta, V.K. et al. (1996) Identification of the sheep homologue of the monocyte cell surface molecule--CD14. Vet Immunol. Immunopathol. 51: 89-99, 4. Jacobsen, C.N. et al. (1993) Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species. Vet. Immunol. Immunopathol. 39: 461-466, 5. Sopp, P. et al. (1997) Cross-reactivity of monoclonal antibodies to defined human leucocyte differentiation antigens with bovine cells. Vet. Immunol. Immunopathol. 56: 11-25, 6. Arriens, M.A. et al. (1996) Cross reactivity of anti-human CD monoclonal antibodies with porcine leukocytes. Vet. Immunol. Immunopathol. 54: 113, 7. Werling, D et al. (1998) Analysis of the phenotype and phagocytic activity of monocytes/macrophages from cattle infected with the bovine leukaemia virus. Vet. Immunol. Immunopathol. 62:185-195, 8. Willett, B. et al. (2003) Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection. J. Virol. 77: 709 - 712, 9. Yang, H. et al. (2003) Antibody to CD14 like CXCR4-specific antibody 12G5 could inhibit CXCR4-dependent chemotaxis and HIV Env-mediated cell fusion. Immunol. Letters 88: 27-30.

Other Notes

Small volumes of anti-CD14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD14. It may not necessarily be applicable to this product.

NCBI GI #
4557417
NCBI GeneID
929
NCBI Accession #
NP_000582.1
UniProt Primary Accession #
P08571
UniProt Secondary Accession #
Q53XT5; Q96FR6; Q96L99; Q9UNS3
UniProt Related Accession #
P08571
GenBank Nucleotide #
NM_000591.3
NCBI Official Full Name
monocyte differentiation antigen CD14
NCBI Official Synonym Full Names
CD14 molecule
NCBI Official Symbol
CD14
UniProt Protein Name
Monocyte differentiation antigen CD14
UniProt Synonym Protein Names
Myeloid cell-specific leucine-rich glycoprotein
Protein Family
Monocyte differentiation antigen
UniProt Gene Name
CD14
UniProt Entry Name
CD14_HUMAN
NCBI Protein Information
monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD14 antibody

 Reference Product  PubMed Publications
 TLR4 antibody  >1220 publications with CD14 and TLR4
 TLR2 antibody  >654 publications with CD14 and TLR2
 LBP antibody  >405 publications with CD14 and LBP
 ITGB2 antibody  >307 publications with CD14 and ITGB2
 LY96 antibody  >136 publications with CD14 and LY96
 TLR1 antibody  >89 publications with CD14 and TLR1
 LY86 antibody  >9 publications with CD14 and LY86
 TICAM2 antibody  >8 publications with CD14 and TICAM2

Pathways associated with anti-CD14 antibody

 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Activation Of IRF3/IRF7 Mediated By TBK1/IKK Epsilon Pathway antibodies  Activation Of IRF3/IRF7 Mediated By TBK1/IKK Epsilon Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 IKK Complex Recruitment Mediated By RIP1 Pathway antibodies  IKK Complex Recruitment Mediated By RIP1 Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram

Diseases associated with anti-CD14 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2154 publications with CD14 and Necrosis
 Inflammation Antibodies  >1973 publications with CD14 and Inflammation
 Neoplasms Antibodies  >1417 publications with CD14 and Neoplasms
 Cardiovascular Diseases Antibodies  >553 publications with CD14 and Cardiovascular Diseases
 Lung Diseases Antibodies  >481 publications with CD14 and Lung Diseases
 Nervous System Diseases Antibodies  >320 publications with CD14 and Nervous System Diseases
 Liver Diseases Antibodies  >310 publications with CD14 and Liver Diseases
 Atherosclerosis Antibodies  >259 publications with CD14 and Atherosclerosis
 Drug Toxicity Antibodies  >240 publications with CD14 and Drug Toxicity
 Asthma Antibodies  >235 publications with CD14 and Asthma

Organs/Tissues associated with anti-CD14 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6862 publications with CD14 and Blood
 Bone Antibodies  >1209 publications with CD14 and Bone
 Vascular Antibodies  >744 publications with CD14 and Vascular
 Liver Antibodies  >555 publications with CD14 and Liver
 Lung Antibodies  >537 publications with CD14 and Lung
 Kidney Antibodies  >299 publications with CD14 and Kidney
 Brain Antibodies  >268 publications with CD14 and Brain
 Muscle Antibodies  >248 publications with CD14 and Muscle
 Heart Antibodies  >246 publications with CD14 and Heart
 Embryonic Tissue Antibodies  >205 publications with CD14 and Embryonic Tissue
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