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CSNK1G3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS625846

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in… More details

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Product Overview

Online Datasheet in PDF
Product Name
CSNK1G3, Polyclonal Antibody
Full Product Name
CSNK1G3, CT (Casein Kinase I Isoform gamma-3, CKI-gamma 3)
Product Gene Name
anti-CSNK1G3 antibody
Product Synonym Names
Anti -CSNK1G3, CT (Casein Kinase I Isoform gamma-3, CKI-gamma 3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human CK1g3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
51,389 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (122847793..122952465). Location: 5q23
OMIM
604253
3D Structure
ModBase 3D Structure for Q9Y6M4
Immunogen
Synthetic peptide selected from the C-terminal region of human CK1g3 (KLH).

Product Categories/Family for anti-CSNK1G3 antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-CSNK1G3 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CSNK1G3 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-CSNK1G3 antibody

Western blot analysis of anti-CK1g3 Pab in placenta lysate. CK1g3 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Rabbit Anti-CSNK1G3 Polyclonal Antibody – Cat# MBS625846

Immunohistochemistry (IHC) of anti-CSNK1G3 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-CSNK1G3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS625846

Other Notes

Small volumes of anti-CSNK1G3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSNK1G3 purchase

MBS625846 is an antibody targeting CSNK1G3. Also known as CSNK1G3, CT (Casein Kinase I Isoform gamma-3, CKI-gamma 3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CSNK1G3. It may not necessarily be applicable to this product.

NCBI GI #
113462010
NCBI GeneID
1456
NCBI Accession #
NP_001038188.1
UniProt Primary Accession #
Q9Y6M4
UniProt Secondary Accession #
Q86WZ7; Q9Y6M3
UniProt Related Accession #
Q9Y6M4
GenBank Nucleotide #
NM_001044723.1
NCBI Official Full Name
casein kinase I isoform gamma-3 isoform 4
NCBI Official Synonym Full Names
casein kinase 1, gamma 3
NCBI Official Symbol
CSNK1G3
UniProt Protein Name
Casein kinase I isoform gamma-3
Protein Family
Casein kinase
UniProt Gene Name
CSNK1G3
UniProt Entry Name
KC1G3_HUMAN
NCBI Protein Information
casein kinase I isoform gamma-3; CKI-gamma 3; OTTHUMP00000159174; OTTHUMP00000159175; OTTHUMP00000223000; OTTHUMP00000223001; OTTHUMP00000223002; OTTHUMP00000227071

NCBI Summary for CSNK1G3

This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
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UniProt Comments for CSNK1G3

CK1G3: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, CK1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 5q23

Cellular Component: cytoplasm; nucleus

Molecular Function: protein serine/threonine kinase activity; ATP binding; protein kinase activity

Biological Process: regulation of cell shape; peptidyl-serine phosphorylation; Wnt receptor signaling pathway; protein modification process; endocytosis; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CSNK1G3 antibody

 Products by Pathway  Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
 Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies  Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 P53 Pathway antibodies  P53 Pathway Diagram

Diseases associated with anti-CSNK1G3 antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >1 publications with CSNK1G3 and Death

Organs/Tissues associated with anti-CSNK1G3 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >1 publications with CSNK1G3 and Testis
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