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MIPEP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS625919

MIPEP performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. It… More details

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Product Overview

Online Datasheet in PDF
Product Name
MIPEP, Polyclonal Antibody
Full Product Name
MIPEP, ID (MIP, HMIP, Mitochondrial Intermediate Peptidase, MIPEP)
Product Gene Name
Product Synonym Names
Anti -MIPEP, ID (MIP, HMIP, Mitochondrial Intermediate Peptidase, MIPEP)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human MIPEP.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
80,641 Da
Chromosome Location
Chromosome: 13; NC_000013.10 (24304328..24463587, complement). Location: 13q12
OMIM
602241
3D Structure
ModBase 3D Structure for Q99797
Immunogen
Synthetic peptide selected from the center region of human MIPEP (KLH).
Applications Tested/Suitable for anti-MIPEP antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MIPEP antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50

Western Blot (WB) of anti-MIPEP antibody

Western blot analysis of anti-MIPEP Antibody (Center) in 293 cell line lysates (35ug/lane). MIPEP (arrow) was detected using the purified Pab.
Rabbit Anti-MIPEP Polyclonal Antibody – Cat# MBS625919

Immunohistochemistry (IHC) of anti-MIPEP antibody

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with MIPEP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-MIPEP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS625919

Other Notes

Small volumes of anti-MIPEP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIPEP purchase

MBS625919 is an antibody targeting MIPEP. Also known as MIPEP, ID (MIP, HMIP, Mitochondrial Intermediate Peptidase, MIPEP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MIPEP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mitochondrial intermediate peptidase
NCBI Official Synonym Full Names
mitochondrial intermediate peptidase
NCBI Official Symbol
MIPEP
NCBI Official Synonym Symbols
MIP; HMIP
UniProt Protein Name
Mitochondrial intermediate peptidase
UniProt Gene Name
MIPEP
UniProt Synonym Gene Names
MIP
UniProt Entry Name
MIPEP_HUMAN
NCBI Protein Information
mitochondrial intermediate peptidase; OTTHUMP00000018121

NCBI Summary for MIPEP

The product of this gene performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This gene may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia. [provided by RefSeq]
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UniProt Comments for MIPEP

MIPEP: Cleaves proteins, imported into the mitochondrion, to their mature size. Belongs to the peptidase M3 family.

Protein type: EC 3.4.24.59; Mitochondrial; Protease

Chromosomal Location of Human Ortholog: 13q12

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: metalloendopeptidase activity; metal ion binding

Biological Process: mitochondrial protein processing; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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