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SKIV2L2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS626111

MBS626111 is an antibody targeting SKIV2L2. Also known as SKIV2L2, ID (ATP-dependent Helicase SKIV2L2, Superkiller Viralicidic Activity 2-like 2, KIAA0052). Reactive in Human. Host: Rabbit. SKIV2L2 may be involved in pre-mRNA splicing. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SKIV2L2, Polyclonal Antibody
Full Product Name
SKIV2L2, ID (ATP-dependent Helicase SKIV2L2, Superkiller Viralicidic Activity 2-like 2, KIAA0052)
Product Gene Name
Product Synonym Names
Anti -SKIV2L2, ID (ATP-dependent Helicase SKIV2L2, Superkiller Viralicidic Activity 2-like 2, KIAA0052)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SKIV2L2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
117,805 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (54603576..54721409). Location: 5q11.2
3D Structure
ModBase 3D Structure for P42285
Immunogen
Synthetic peptide selected from the Center region of human SKIV2L2 (KLH).

Product Categories/Family for anti-SKIV2L2 antibody

Applications Tested/Suitable for anti-SKIV2L2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SKIV2L2 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-SKIV2L2 antibody

Western blot analysis of SKIV2L2 Antibody (Center) in MCF-7 cell line lysates (35ug/lane). SKIV2L2 (arrow) was detected using the purified Pab.
Rabbit Anti-SKIV2L2 Polyclonal Antibody – Cat# MBS626111

Immunohistochemistry (IHC) of anti-SKIV2L2 antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with SKIV2L2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-SKIV2L2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS626111

Flow Cytometry (FC/FACS) of anti-SKIV2L2 antibody

SKIV2L2 Antibody (Center) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-SKIV2L2 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS626111

Other Notes

Small volumes of anti-SKIV2L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SKIV2L2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
superkiller viralicidic activity 2-like 2
NCBI Official Synonym Full Names
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
NCBI Official Symbol
SKIV2L2
NCBI Official Synonym Symbols
Dob1; Mtr4; fSAP118; KIAA0052; MGC142069
UniProt Protein Name
Superkiller viralicidic activity 2-like 2
UniProt Synonym Protein Names
ATP-dependent helicase SKIV2L2
UniProt Gene Name
SKIV2L2
UniProt Synonym Gene Names
KIAA0052; Mtr4
UniProt Entry Name
SK2L2_HUMAN
NCBI Protein Information
superkiller viralicidic activity 2-like 2; OTTHUMP00000122510; ATP-dependent helicase SKIV2L2; functional spliceosome-associated protein 118

UniProt Comments for SKIV2L2

SKIV2L2: May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Belongs to the helicase family. SKI2 subfamily.

Protein type: DNA-binding; Helicase; Spliceosome; EC 3.6.4.13; Nucleolus

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: nucleoplasm; nucleolus; exosome (RNase complex); nucleus

Molecular Function: protein binding; helicase activity; ATP binding

Biological Process: nuclear mRNA splicing, via spliceosome; maturation of 5.8S rRNA
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SKIV2L2 antibody

 Reference Product  PubMed Publications
 MPP6 antibody  >1 publications with SKIV2L2 and MPP6

Pathways associated with anti-SKIV2L2 antibody

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