Rabbit Anti-HAO1 Polyclonal Antibody – Cat# MBS626236

Western blot analysis of HAO1 Antibody (Center) in mouse liver tissue lysates (35ug/lane). HAO1 (arrow) was detected using the purified Pab.

HAO1 Antibody – Rabbit Polyclonal

Name: HAO1 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS626236
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS626236

HAO1 is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HAO1, Polyclonal Antibody

Full Product Name

HAO1 (Hydroxyacid Oxidase 1, HAOX1, Glycolate Oxidase, GOX, GOX1, MGC142225, MGC142227)

Product Gene Name

anti-HAO1 antibody

Product Synonym Names

Anti -HAO1 (Hydroxyacid Oxidase 1, HAOX1, Glycolate Oxidase, GOX, GOX1, MGC142225, MGC142227)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human HAO1. Species Crossreactivity: mouse.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

40,924 Da

Chromosome Location

Chromosome: 20; NC_000020.10 (7863631..7921093, complement). Location: 20p12

OMIM

605023

3D Structure

ModBase 3D Structure for Q9UJM8

Immunogen

Synthetic peptide selected from the Center region of human HAO1 (KLH).

Product Categories/Family for anti-HAO1 antibody

Antibodies; Abs to Enzymes; Oxidase

Applications Tested/Suitable for anti-HAO1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-HAO1 antibody

Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Other Notes

Small volumes of anti-HAO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAO1 purchase

MBS626236 is an antibody targeting HAO1. Also known as HAO1 (Hydroxyacid Oxidase 1, HAOX1, Glycolate Oxidase, GOX, GOX1, MGC142225, MGC142227). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HAO1. It may not necessarily be applicable to this product.

NCBI GI #

11068137

NCBI GeneID

54363

NCBI Accession #

NP_060015.1

UniProt Primary Accession #

Q9UJM8

UniProt Secondary Accession #

Q14CQ0; Q9UPZ0; Q9Y3I7

UniProt Related Accession #

Q9UJM8

GenBank Nucleotide #

NM_017545.2

NCBI Official Full Name

hydroxyacid oxidase 1

NCBI Official Synonym Full Names

hydroxyacid oxidase (glycolate oxidase) 1

NCBI Official Symbol

HAO1

NCBI Official Synonym Symbols

GOX; GOX1; HAOX1; MGC142225; MGC142227

UniProt Protein Name

Hydroxyacid oxidase 1

UniProt Synonym Protein Names

Glycolate oxidase

Protein Family

Hydroxyacid oxidase

UniProt Gene Name

HAO1

UniProt Synonym Gene Names

GOX1; HAOX1

UniProt Entry Name

HAOX1_HUMAN

NCBI Protein Information

hydroxyacid oxidase 1; glycolate oxidase; OTTHUMP00000030231; (S)-2-hydroxy-acid oxidase

NCBI Summary for HAO1

This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq]

UniProt Comments for HAO1

HAO1: Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2- hydroxy octanoate. Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

Protein type: EC 1.1.3.15; Oxidoreductase; Carbohydrate Metabolism - glyoxylate and dicarboxylate

Chromosomal Location of Human Ortholog: 20p12

Cellular Component: peroxisomal matrix; peroxisome

Molecular Function: glycolate oxidase activity; FMN binding; glyoxylate oxidase activity; (S)-2-hydroxy-acid oxidase activity; receptor binding

Biological Process: glyoxylate metabolic process; response to oxidative stress; glycolate catabolic process; fatty acid alpha-oxidation

Research Articles on HAO1

1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-HAO1 antibody

Products by Pathway	Pathway Diagram
Glyoxylate And Dicarboxylate Metabolism Pathway antibodies	Glyoxylate And Dicarboxylate Metabolism Pathway Diagram
Glyoxylate And Dicarboxylate Metabolism Pathway antibodies	Glyoxylate And Dicarboxylate Metabolism Pathway Diagram
Glyoxylate Metabolism Pathway antibodies	Glyoxylate Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Peroxisome Pathway antibodies	Peroxisome Pathway Diagram
Peroxisome Pathway antibodies	Peroxisome Pathway Diagram

Diseases associated with anti-HAO1 antibody

Disease Name	Pubmed Publications
Reperfusion Injury Antibodies	>1 publications with HAO1 and Reperfusion Injury
Leukemia Antibodies	>1 publications with HAO1 and Leukemia
Neoplasms Antibodies	>1 publications with HAO1 and Neoplasms
Fatty Liver Antibodies	>1 publications with HAO1 and Fatty Liver

Organs/Tissues associated with anti-HAO1 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with HAO1 and Liver
Kidney Antibodies	>1 publications with HAO1 and Kidney
Pancreas Antibodies	>1 publications with HAO1 and Pancreas