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PARP12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS626385

Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large… More details

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Product Overview

Online Datasheet in PDF
Product Name
Parp12, Polyclonal Antibody
Full Product Name
Parp12, NT (Poly [ADP-ribose] Polymerase 12, PARP-12, Zinc Finger CCCH Domain-containing Protein 1, ZC3HDC1)
Product Gene Name
anti-PARP12 antibody
Product Synonym Names
Anti -Parp12, NT (Poly [ADP-ribose] Polymerase 12, PARP-12, Zinc Finger CCCH Domain-containing Protein 1, ZC3HDC1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human NFATC2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
79,064 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (139723544..139764086, complement). Location: 7q34
OMIM
612481
3D Structure
ModBase 3D Structure for Q9H0J9
Immunogen
Synthetic peptide selected from the N-terminal region of human Parp12 (KLH).

Product Categories/Family for anti-PARP12 antibody

Antibodies; Abs to Enzymes; Polymerase
Applications Tested/Suitable for anti-PARP12 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-PARP12 antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:10-1:50

Western Blot (WB) of anti-PARP12 antibody

Parp12 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Parp12 antibody detected the Parp12 protein (arrow).
Rabbit Anti-PARP12 Polyclonal Antibody – Cat# MBS626385

Immunohistochemistry (IHC) of anti-PARP12 antibody

Parp12 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Parp12 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-PARP12 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS626385

Flow Cytometry (FC/FACS) of anti-PARP12 antibody

Parp12 Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-PARP12 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS626385

Other Notes

Small volumes of anti-PARP12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PARP12 purchase

MBS626385 is an antibody targeting PARP12. Also known as Parp12, NT (Poly [ADP-ribose] Polymerase 12, PARP-12, Zinc Finger CCCH Domain-containing Protein 1, ZC3HDC1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PARP12. It may not necessarily be applicable to this product.

NCBI GI #
530387095
NCBI GeneID
64761
NCBI Accession #
XP_005250097.1
UniProt Primary Accession #
Q9H0J9
UniProt Secondary Accession #
Q9H610; Q9NP36; Q9NTI3
UniProt Related Accession #
Q9H0J9
GenBank Nucleotide #
XM_005250040.1
NCBI Official Full Name
poly
NCBI Official Synonym Full Names
poly (ADP-ribose) polymerase family, member 12
NCBI Official Symbol
PARP12
NCBI Official Synonym Symbols
ZC3H1; ARTD12; MST109; MSTP109; ZC3HDC1
UniProt Protein Name
Poly [ADP-ribose] polymerase 12
UniProt Synonym Protein Names
ADP-ribosyltransferase diphtheria toxin-like 12; ARTD12; Zinc finger CCCH domain-containing protein 1
Protein Family
Poly [ADP-ribose] polymerase
UniProt Gene Name
PARP12
UniProt Synonym Gene Names
ZC3HDC1; PARP-12; ARTD12
UniProt Entry Name
PAR12_HUMAN
NCBI Protein Information
poly [ADP-ribose] polymerase 12; poly [ADP-ribose] polymerase 12; zinc finger CCCH type domain containing 1; zinc finger CCCH domain-containing protein 1; ADP-ribosyltransferase diphtheria toxin-like 12

UniProt Comments for PARP12

PARP12:

Protein type: Transferase; EC 2.4.2.30

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: nucleus

Molecular Function: metal ion binding; NAD+ ADP-ribosyltransferase activity

Biological Process: metabolic process

Research Articles on PARP12

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PARP12 antibody

 Reference Product  PubMed Publications
 DDX58 antibody  >1 publications with PARP12 and DDX58

Diseases associated with anti-PARP12 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with PARP12 and Nervous System Diseases

Organs/Tissues associated with anti-PARP12 antibody

 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >2 publications with PARP12 and Uterus
 Blood Antibodies  >1 publications with PARP12 and Blood
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