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NUAK2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS626400

Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NUAK2, Polyclonal Antibody
Full Product Name
NUAK2, NT (NUAK Family SNF1-like Kinase 2, SNF1/AMP Kinase-related Kinase, SNARK)
Product Gene Name
Product Synonym Names
Anti -NUAK2, NT (NUAK Family SNF1-like Kinase 2, SNF1/AMP Kinase-related Kinase, SNARK)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human NUAK2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
69,612 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (205271191..205290883, complement). Location: 1q32.1
OMIM
608131
3D Structure
ModBase 3D Structure for Q9H093
Immunogen
Synthetic peptide selected from the N-terminal region of human NUAK2 (KLH).
Applications Tested/Suitable for anti-NUAK2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-NUAK2 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100

Western Blot (WB) of anti-NUAK2 antibody

Western blot analysis of NUAK2 (arrow) using rabbit polyclonal NUAK2 Antibody (N-term) (RB08560). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NUAK2 gene (Lane 2) (Origene Technologies).
Rabbit Anti-NUAK2 Polyclonal Antibody – Cat# MBS626400

Other Notes

Small volumes of anti-NUAK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NUAK2 purchase

MBS626400 is an antibody targeting NUAK2. Also known as NUAK2, NT (NUAK Family SNF1-like Kinase 2, SNF1/AMP Kinase-related Kinase, SNARK). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NUAK2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
NUAK family SNF1-like kinase 2
NCBI Official Synonym Full Names
NUAK family, SNF1-like kinase, 2
NCBI Official Symbol
NUAK2
NCBI Official Synonym Symbols
SNARK
UniProt Protein Name
NUAK family SNF1-like kinase 2
UniProt Synonym Protein Names
Omphalocele kinase 2; SNF1/AMP kinase-related kinase
UniProt Gene Name
NUAK2
UniProt Synonym Gene Names
OMPHK2; SNARK; SNARK
UniProt Entry Name
NUAK2_HUMAN
NCBI Protein Information
NUAK family SNF1-like kinase 2; omphalocele kinase 2; SNF1/AMP kinase-related kinase; SNF1/AMP activated protein kinase

UniProt Comments for NUAK2

NuaK2: a Ca(2+)/calmodulin-dependent protein kinase of the CAMKL family.

Protein type: Protein kinase, CAMK; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CAMK group; CAMKL family; NuaK subfamily

Chromosomal Location of Human Ortholog: 1q32.1

Molecular Function: protein serine/threonine kinase activity; protein binding; magnesium ion binding; ATP binding

Biological Process: cellular response to glucose starvation; apoptosis; actin cytoskeleton organization and biogenesis; protein amino acid phosphorylation; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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