KDM2B Antibody – Rabbit Polyclonal

FBXL10 is a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. It preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. FBXL10 is a member of the F-box protein family which is characterized by an approximately 40aa motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL10 belongs to the Fbls class.

Small volumes of anti-KDM2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS626401 is an antibody targeting KDM2B. Also known as KDM2B, CT (Lysine-specific Demethylase 2B, JmjC Domain-containing Histone Demethylation Protein 1B, [Histone-H3]-lysine-36 Demethylase 1B, F-box/LRR-repeat Protein 10, F-box and Leucine-rich Repeat Protein 10, F-box Protein FBL10, Protein JEMMA, Jumonji D. Reactive in Human. Host: Rabbit.