Rabbit Anti-OPRD1 Polyclonal Antibody – Cat# MBS626408

Opioid Receptor, Delta, Aa360-372 (OPRD1) Antibody – Rabbit Polyclonal

Name: OPRD1 Antibody; Polyclonal; Rabbit; Human/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS626408
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS626408

The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In… More details

$580 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Opioid Receptor, delta, aa360-372 (OPRD1), Polyclonal Antibody

Full Product Name

Opioid Receptor, delta, CT, aa360-372

Product Gene Name

anti-OPRD1 antibody

Product Synonym Names

Anti -Opioid Receptor, delta, CT, aa360-372

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Rat

Form/Format

Supplied as a lyophilized powder. Reconstitute with 100ul sterile PBS, 10mg/ml BSA.

Purity/Purification

Serum
Serum

Specificity

Recognizes human Delta Opioid Receptor (360-372)

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS, 10mg/ml BSA. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

40,369 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (29138654..29190208). Location: 1p36.1-p34.3

OMIM

165195

3D Structure

ModBase 3D Structure for P41143

Immunogen

Synthetic peptide corresponding to the carboxyl terminal of human delta opioid receptor covalently attached to a carrier protein.

Product Categories/Family for anti-OPRD1 antibody

Antibodies; Abs to Opioid Receptors; Agonists

Applications Tested/Suitable for anti-OPRD1 antibody

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-OPRD1 antibody

Suitable for ELISA, Immunohistochemistry and Western Blot.
Dilution: Immunohistochemistry (ABC): 1:800 Stains specific cells in various regions of PLP fixed rat brain sections known to express the delta opioid receptor.
Western Blot: 1:800; Band at ~55kD is observed using whole rat brain homogenate.

Other Notes

Small volumes of anti-OPRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OPRD1 purchase

MBS626408 is an antibody targeting OPRD1. Also known as Opioid Receptor, delta, CT, aa360-372. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for OPRD1. It may not necessarily be applicable to this product.

NCBI GI #

119628077

NCBI GeneID

4985

UniProt Primary Accession #

P41143

UniProt Secondary Accession #

B5B0B8

UniProt Related Accession #

P41143

NCBI Official Full Name

opioid receptor, delta 1

NCBI Official Synonym Full Names

opioid receptor, delta 1

NCBI Official Symbol

OPRD1

NCBI Official Synonym Symbols

OPRD

UniProt Protein Name

Delta-type opioid receptor

Protein Family

Delta-type opioid receptor

UniProt Gene Name

OPRD1

UniProt Synonym Gene Names

OPRD

UniProt Entry Name

OPRD_HUMAN

NCBI Protein Information

delta-type opioid receptor; DOR-1; D-OR-1; OTTHUMP00000003778; delta opioid receptor 1

UniProt Comments for OPRD1

DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.1-p34.3

Cellular Component: postsynaptic membrane; neuron projection; integral to plasma membrane; cytoplasm; plasma membrane; nerve terminal; vesicle; intrinsic to plasma membrane; lipid raft

Molecular Function: neuropeptide binding; protein binding; opioid receptor activity

Biological Process: adult locomotory behavior; activation of CREB transcription factor; regulation of calcium ion transport; sensory perception of pain; positive regulation of peptidyl-serine phosphorylation; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of protein oligomerization; G-protein coupled receptor protein signaling pathway; synaptic transmission; regulation of mitochondrial membrane potential; neuropeptide signaling pathway; protein import into nucleus, translocation; immune response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein signaling, adenylate cyclase inhibiting pathway; regulation of sensory perception of pain

Research Articles on OPRD1

1. data suggest that an increased constitutive internalization and/or concurrent signaling of the delta-opioid receptor-Cys27 variant affects APP processing through altered endocytic trafficking of APP

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OPRD1 antibody

Reference Product	PubMed Publications
OPRM1 antibody	>17 publications with OPRD1 and OPRM1
OPRK1 antibody	>12 publications with OPRD1 and OPRK1
GNAZ antibody	>1 publications with OPRD1 and GNAZ
ARRB2 antibody	>1 publications with OPRD1 and ARRB2

Pathways associated with anti-OPRD1 antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with anti-OPRD1 antibody

Disease Name	Pubmed Publications
Pain Antibodies	>9 publications with OPRD1 and Pain
Autistic Disorder Antibodies	>1 publications with OPRD1 and Autistic Disorder
Child Development Disorders, Pervasive Antibodies	>1 publications with OPRD1 and Child Development Disorders, Pervasive
Anxiety Disorders Antibodies	>1 publications with OPRD1 and Anxiety Disorders
Hepatitis Antibodies	>1 publications with OPRD1 and Hepatitis

Organs/Tissues associated with anti-OPRD1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>7 publications with OPRD1 and Brain