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SULT1B1 Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS626581

Catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active… More details

$1105 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SULT1B1, Polyclonal Antibody
Full Product Name
SULT1B1 (Sulfotransferase Family, Cytosolic, 1B, Member 1, Sulfotransferase 1B1, ST1B1, Sulfotransferase 1B2, ST1B2, Thyroid Hormone Sulfotransferase, ST1B2, SULT1B2)
Product Gene Name
Product Synonym Names
Anti -SULT1B1 (Sulfotransferase Family, Cytosolic, 1B, Member 1, Sulfotransferase 1B1, ST1B1, Sulfotransferase 1B2, ST1B2, Thyroid Hormone Sulfotransferase, ST1B2, SULT1B2)
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with sterile PBS.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SULT1B1. Shows 5% cross-reactivity with rhSULT1A1 and rhSULT1A3 and less than 2% cross-reactivity with rhSULT2A1, rhSULT4A1, rhSULT2B1 and rhSUL T1E1.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
34,899 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (70592686..70626430, complement). Location: 4q13.3
OMIM
608436
3D Structure
ModBase 3D Structure for O43704
Immunogen
Purified, E. coli-derived, recombinant human Sulfotransferase 1B1 (aa2-296).
Applications Tested/Suitable for anti-SULT1B1 antibody
Western Blot (WB)
Application Notes for anti-SULT1B1 antibody
Suitable for use in ELISA, Neutralization, and Western Blot.
Dilution: Western Blot: 1ug/ml
ELISA: 0.5-1ug/ml

SDS-Page of anti-SULT1B1 antibody

Detection of SULT1B1: Cell and tissue lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with 1ug/ml sheep anti-hSULT1B1.
Sheep Anti-SULT1B1 Polyclonal Antibody – Cat# MBS626581

Other Notes

Small volumes of anti-SULT1B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SULT1B1 purchase

MBS626581 is an antibody targeting SULT1B1. Also known as SULT1B1 (Sulfotransferase Family, Cytosolic, 1B, Member 1, Sulfotransferase 1B1, ST1B1, Sulfotransferase 1B2, ST1B2, Thyroid Hormone Sulfotransferase, ST1B2, SULT1B2). Reactive in Human. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for SULT1B1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sulfotransferase family cytosolic 1B member 1
NCBI Official Synonym Full Names
sulfotransferase family, cytosolic, 1B, member 1
NCBI Official Symbol
SULT1B1
NCBI Official Synonym Symbols
ST1B1; ST1B2; SULT1B2; MGC13356
UniProt Protein Name
Sulfotransferase family cytosolic 1B member 1
UniProt Synonym Protein Names
Sulfotransferase 1B2; ST1B2; Thyroid hormone sulfotransferase
UniProt Gene Name
SULT1B1
UniProt Synonym Gene Names
ST1B2; SULT1B2
UniProt Entry Name
ST1B1_HUMAN
NCBI Protein Information
sulfotransferase family cytosolic 1B member 1; OTTHUMP00000159773; sulfotransferase 1B1; sulfotransferase 1B2; thyroid hormone sulfotransferase

NCBI Summary for SULT1B1

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq]
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UniProt Comments for SULT1B1

SULT1B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine. Belongs to the sulfotransferase 1 family.

Protein type: Transferase; EC 2.8.2.-

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: cytosol

Molecular Function: sulfotransferase activity; aryl sulfotransferase activity

Biological Process: steroid metabolic process; biogenic amine metabolic process; epithelial cell differentiation; flavonoid metabolic process; xenobiotic metabolic process; sulfation; thyroid hormone metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; phenol metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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