Mouse Anti-Ku Monoclonal Antibody – Cat# MBS6266572

Formalin-fixed, paraffin-embedded human tonsil stained with Ku Ab using peroxidase-conjugate and AEC chromogen. Note nuclear staining of the cells.

Ku Antibody – Mouse Monoclonal

Name: Ku Antibody; Monoclonal; Mouse; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6266572
Price: 945 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6266572

MBS6266572 is an antibody targeting Ku. Also known as Ku, p70, p80 (BSA & Azide Free) (FITC). Reactive in Human, Monkey, Mouse, Rat, Xenopus. Host: Mouse. More details

$945 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ku, Monoclonal Antibody

Full Product Name

Ku, p70, p80 (BSA & Azide Free) (FITC)

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

3F247

Host

Mouse

Species Reactivity

Human, Monkey, Mouse, Rat, Xenopus

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).

Purity/Purification

Purified by Ammonium Sulfate Precipitation

Specificity

Recognizes Ku, p70, p80. Species Crossreactivity: human, monkey, xenopus. mouse and rat (Immunoprecipitation only). Does not react with bovine and rabbit.

Preparation and Storage

Store at -20 degree C.

Immunogen

Human B cell nuclei from plasmacytoid 2p68 cells

Conjugate

FITC

Product Categories/Family for anti-Ku antibody

Antibodies; Transcription Factors

Applications Tested/Suitable for anti-Ku antibody

Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product References and Citations for anti-Ku antibody

1. Wang J, et. al. Molecular Biology Reports, 1993, 18(1):15-28. 2. Reeves WH, et. al. Journal of Experimental Medicine, 1985, 161(1):18-39. Additional: 1. Griffin W, Torrance H, Rodda DJ, Prefontaine GG, Pope L, Hache RJG. Sequence-specific DNA binding by autoantigen and its effects on transcription. Nature, 1996, 380:265-8. 2. Ajmani AK; Satoh M; Reap E; Cohen PL; Reeves WH. Absence of autoantigen Ku in mature human neutrophils and human promyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis. Journal of Experimental Medicine, 1995 Jun 1, 181(6):2049-58. 3. Boubnov NV; Hall KT; Wills Z; Lee SE; He DM; Benjamin DM; Pulaski CR; Band H; Reeves W; Hendrickson EA; et al. Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen. Proceedings of the National Academy of Sciences of the United States of America, 1995 Jan 31, 92(3):890-4. 4. DiCroce PA; Krontiris TG. The BCL2 major breakpoint region is a sequence-and cell-cycle-specific binding site of the Ku antigen. Proceedings of the National Academy of Sciences of the United States of America, 1995 Oct 24, 92(22):10137-41. 5. Wang J; Chou CH; Blankson J; Satoh M; Knuth MW; Eisenberg RA; Pisetsky DS; Reeves WH. Murine monoclonal antibodies specific for conserved and nonconserved antigenic determinants of the human and murine Ku autoantigens. Molecular Biology Reports, 1993 Jun, 18(1):15-28. 6. Reeves WH. Use of monoclonal antibodies for the characterization of novel DNA-binding proteins recognized by human autoimmune sera. Journal of Experimental Medicine, 1985 Jan 1, 161(1):18-39.

Other Notes

Small volumes of anti-Ku antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ku. It may not necessarily be applicable to this product.

Protein Family

Kunitz/BPTI-like toxin

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.