c-erbB3 Antibody – Mouse Monoclonal

MBS6267094 is an antibody targeting c-erbB3. Also known as c-erbB3 (HER 3, ErbB3) (BSA & Azide Free) (MaxLight 405). Reactive in Bovine, Human, Mouse, Rat. Host: Mouse.

1. Prigent SA and Lemoine NR. The type I (EGFR-related) family of growth factor receptors and their ligands. Progress in Growth Factor Research, 1992, 4: 1-24. 2. Plowman GD, Culouscou JM, Whitney GS, Green JM, Carlton GW, Foy L, Neubauer MG, and Shoyab M. Proc Natl Acad Sci USA, 1993, 90: 1746-50. 3. Krauss MH, Issing W, Miki T, Popescu NC, and Aaronson SA. Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors. Proc Natl Acad Sci USA, 1989, 86: 9193-7. 4. Plowman GD, Whitney GS, Neubauer MG, Green JM, McDonald VL, Todaro GJ, and Shoyab M. Molecular cloning and expression of an additional epidermal growth factor receptor-related gene. Proc Natl Acad Sci, 1990, 87: 4905-9. 5. Kraus MH, Fedi P, Starks V, Muraro R, Aaronson SA. Demonstration of ligand-dependent signaling by the erbB-3 tyrosine kinase and its constitutive activation in human breast tumor cells. Proc Natl Acad Sci USA, 1993, 90;2900-4. 6. Katoh M, Yazaki Y, Sugimura T, Terada M. c-erbB-3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. Biochem Biophys Res Commun, 1993, 192(3); 1189-97. 7. Fedi P, Pierce JH, Di Fiore PP, Kraus MH. Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase Cg or GTPase-activating protein, distinguishes erbB-3 signaling from that of other erbB/EGFR family members. Mol Cell Biol, 1994, 14(1); 492-500. 8. Guy PM, Platko JV, Cantley LC, Cerione RA, Carraway KL 3rd. Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity. Proc Natl Acad Sci USA, 1994, 91(17):8132-6. 9. Soltoff SP, Carraway KL 3rd, Prigent SA, Gullick WG, Cantley LC. ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Molecular and Cellular Biology, 1994, 14(6):3550-8. 10. Kim HH, Sierke SL, Koland JG. Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product. Journal of Biological Chemistry, 1994, 269(40):24747-55.

Small volumes of anti-c-erbB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.