CD4 Antibody – Mouse Monoclonal

MBS6268464 is an antibody targeting CD4. Also known as CD4 (APC). Reactive in Bovine. Host: Mouse.

1. Bensaid, A. et al. (1991) Individual antigens of cattle. Bovine CD4 (BoCD4). Vet. Immunol. Immunopathol. 27: 51-54. 2. Eskra, L. et al. (1991) Effect of monoclonal antibodies on in vitro function of T-cell subsets. Vet. Immunol. Immunopathol. 27: 215-231. 3. Gutierrez, M. et al. (1999) The detection of CD2+, CD4+, CD8+, and WC1+ T lymphocytes, B cells and macrophages in fixed and paraffin embedded bovine tissue using a range of antigen recovery and signal amplification techniques. Vet. Immunol. Immunopathol. 71: 321-334. 4. Winkler, M. et al (1999) Bovine Herpesvirus 1 Can Infect CD4+ T Lymphocytes and Induce Programmed Cell Death during Acute Infection of Cattle. J Virol. 73:8657-8668. 5. Winkler, M. et al. (2000) Persistence and Reactivation of Bovine Herpesvirus 1 in the Tonsils of Latently Infected Calves. J Virol. 74: 5337-5346. 6. Riondato, F. et al. (2008) Effects of road transportation on lymphocyte subsets in calves Vet J. 175: 364-8. 7. Collins, R.A. et al. (1999) Bovine interleukin-12 and modulation of IFNgamma production. Vet Immunol Immunopathol. 68: 193-207. 8. Liebana, E. et al. (2007) Distribution and activation of T-lymphocyte subsets in tuberculous bovine lymph-node granulomas. Vet Pathol. 44: 366-72. 9. Suhwold, A. et al. (2010) T cell reactions of Eimeria bovis primary and challenge-infected calves. Parasitol Res. 106: 595-605. 10. Rhodes, S.G. et al. (2000) Bovine tuberculosis: immune responses in the peripheral blood and at the site of active disease. Immunology. 99: 195-202. 11. Machugh, N.D. et al. (1997) Identification of two distinct subsets of bovine gamma delta T cells with unique cell surface phenotype and tissue distribution. Immunology. 92: 340-5. 12. Childerstone, A.J. et al. (1999) Demonstration of bovine CD8+ T-cell responses to foot-and-mouth disease virus. J Gen Virol. 80: 663-9. 13. Rhodes, S.G. et al. (2001) Antigen recognition and immunomodulation by gamma delta T cells in bovine tuberculosis. J Immunol. 166: 5604-10. 14. Knowles, G. et al. (1996) Phenotypical characterization of lymphocytes infiltrating regressing papillomas. J Virol. 70: 8451-8. 15. Smyth, A.J. et al. (2001) In vitro responsiveness of gammadelta T cells from Mycobacterium bovis-infected cattle to mycobacterial antigens: predominant involvement of WC1(+) cells. Infect Immun. 69: 89-96. 16. Hein, W.R. and Dudler, L. (1997) TCR gamma delta+ cells are prominent in normal bovine skin and express a diverse repertoire of antigen receptors. Immunology. 91: 58-64. 17. Juleff, N. et al. (2009) Foot-and-mouth disease virus can induce a specific and rapid CD4+ T-cell-independent neutralizing and isotype class-switched antibody response in naïve cattle. J Virol. 83: 3626-36. 18. Hope, J.C. et al. (2005) Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle. Clin Exp Immunol. 141: 432-9. 19. Sopp, P. et al. (2006) Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle. Clin Vaccine Immunol. 13: 1343-8. 20. Sacchini, F. et al. (2011) A minor role of CD4+ T lymphocytes in the control of a primary infection of cattle with Mycoplasma mycoides subsp. mycoides. Vet Res. 42: 77. 21. Skyberg, J.A. et al. (2011) Murine and bovine ?d T cells enhance innate immunity against Brucella abortus infections. PLoS One. 6(7): e21978. 22. Canton, G.J. et al. (2013) Phenotypic characterisation of the cellular immune infiltrate in placentas of cattle following experimental inoculation with Neospora caninum in late gestation. Vet Res. 44: 60.

Small volumes of anti-CD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.