CD45RA Antibody – Mouse Monoclonal

MBS6268526 is an antibody targeting CD45RA. Also known as CD45RA (Leukocyte Common Antigen, LCA, Ly-5 T200) (APC). Reactive in Rat. Host: Mouse.

1. Barclay AN and McCall MN. CD45; from alloantigen to mapping of restricted epitopes using recombinant soluble CD45 isoforms. Biochem. Soc. Trans. 1992 20:161 PubMed 2. Trowbridge IS and Thomas ML. CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 1993 12:85 PubMed 3. Beverley PCL. 1980. in Production and Use of Monoclonal Antibodies in Transplantation Immunology. In Transplantation and Clinical Immunology XI. pp 87-94, eds Touraine JL et al, Excerpta Medica Amsterdam. 4. Kishihara K, Penninger J, Wallace VA, Kundig TM, Kawai K, Wakeham A, Timms E, Pfeffer K, Ohashi PS, Thomas ML and et al. Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice. Cell 1993 74:143 PubMed 5. Morimoto C, Letvin NL, Distaso JA, Aldrich WR and Schlossman SF. The isolation and characterization of the human suppressor inducer T cell subset. J. Immunol. 1985 134:1508 PubMed 6. Okumura M, Matthews RJ, Robb B, Litman GW, Bork P and Thomas ML. Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains. J. Immunol. 1996 157:1569 PubMed 7. Perillo NL, Pace KE, Seilhamer JJ and Baum LG. Apoptosis of T cells mediated by galectin-1. Nature 1995 378:736 PubMed 8. Pingel JT and Thomas ML. Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation. Cell 1989 58:1055 PubMed 9. Pulido R, Cebrian M, Acevedo A, de Landazuri MO and Sanchez-Madrid F. Comparative biochemical and tissue distribution study of four distinct CD45 antigen specificities. J. Immunol. 1988 140:3851 PubMed 10. Roach T, Slater S, Koval M, White L, McFarland EC, Okumura M, Thomas M and Brown E. CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion. Curr. Biol. 1997 7:408 PubMed 11. Terry LA, Brown MH and Beverley PC. The monoclonal antibody, UCHL1, recognizes a 180,000 MW component of the human leucocyte-common antigen, CD45. Immunology 1988 64:331PubMed 12. Tonks NK, Charbonneau H, Diltz CD, Fischer EH and Walsh KA. Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase. Biochemistry 1988 27:8695 PubMed 13. Zapata JM, Pulido R, Acevedo A, Sanchez-Madrid F and de Landazuri MO. Human CD45RC specificity. A novel marker for T cells at different maturation and activation stages. J. Immunol. 1994 152:3852 PubMed

Small volumes of anti-CD45RA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.