Thioredoxin Antibody – Mouse Monoclonal

MBS6269199 is an antibody targeting Thioredoxin. Also known as Thioredoxin (APC). Reactive in Human. Host: Mouse.

1. Perkins, A.V., et al., Placenta 16: 635-642 (1995). 2. Lincoln, D. et al. (2003) The thioredoxin-thioredoxin reductase system: over-expression in human cancer. Anticancer Res. 23: 2425-2434. 3. Stantchev, T.S. et al. (2012) Cell-type specific requirements for thiol/disulfide exchange during HIV-1 entry and infection. Retrovirology. 9: 97. 4. Ma, X. et al. (2001) Regulation of interferon and retinoic acid-induced cell death activation through thioredoxin reductase. J Biol Chem. 276: 24843-54. 5. Ramanathan, R.K. et al. (2007) A Phase I pharmacokinetic and pharmacodynamic study of PX-12, a novel inhibitor of thioredoxin-1, in patients with advanced solid tumors. Clin Cancer Res. 13: 2109-14. 6. Arnold, N.B. et al. (2004) Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer. Cancer Res. 64: 3599-606.7. Kinoshita, T. et al. (2007) Thioredoxin prevents the development and progression of elastase-induced emphysema. Biochem Biophys Res Commun. 354: 712-9. 8. Dorion, S. et al. (2002) Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione S-transferase Mu from Ask1.J Biol Chem. 277: 30792-7. 9. Sensi, M. et al. (2005) Immunogenicity without immunoselection: a mutant but functional antioxidant enzyme retained in a human metastatic melanoma and targeted by CD8(+) T cells with a memory phenotype. Cancer Res. 65: 632-40. 10. Mamoon, N.M. et al. (2007) Multiple cysteine residues are implicated in Janus kinase 2-mediated catalysis.Biochemistry. 46: 14810-8. 11. Agathanggelou, A. et al. (2003) Identification of Novel Gene Expression Targets for the Ras Association Domain Family 1 (RASSF1A) Tumor Suppressor Gene in Non-Small Cell Lung Cancer and Neuroblastoma. Cancer Res. 63: 5344-51. 12. Di Trapani, G. et al. (1998) Production and secretion of thioredoxin from transformed human trophoblast cells. Mol Hum Reprod. 4: 369-75.13. Lopata, A. et al. (2001) Expression and localization of thioredoxin during early implantation in the marmoset monkey. Mol Hum Reprod. 7: 1159-65.

Small volumes of anti-Thioredoxin antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.