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NRXN3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6269934

MBS6269934 is an antibody targeting NRXN3. Also known as NRXN3 (Neurexin-3-alpha, Neurexin III-alpha, C14orf60, KIAA0743) (PE). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$1205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NRXN3, Polyclonal Antibody
Full Product Name
NRXN3 (Neurexin-3-alpha, Neurexin III-alpha, C14orf60, KIAA0743) (PE)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human Neurexin3. Species Crossreactivity: Mouse and rat.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
180
OMIM
600567
3D Structure
ModBase 3D Structure for Q9Y4C0
Immunogen
KLH-conjugated linear peptide corresponding to a stretch of amino acids in the extracellular domain of human Neurexin3, UniProt Accession #Q9Y4C0.
Conjugate
PE
Positive Control
PC12 cell lysate.
Note
Preservative Free

Product Categories/Family for anti-NRXN3 antibody

Applications Tested/Suitable for anti-NRXN3 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-NRXN3 antibody
IHC: 1:500
WB: 1ug/ml.
Applications are based on unconjugated antibody.

Product References and Citations for anti-NRXN3 antibody

1. Dean, C., et al. (2003). 6(7):708-716. 2. Missler, M., et al. (1998). 14(1):20-26.

Other Notes

Small volumes of anti-NRXN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NRXN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neurexin 3 isoform 1
NCBI Official Synonym Full Names
neurexin 3
NCBI Official Symbol
NRXN3
NCBI Official Synonym Symbols
C14orf60
UniProt Protein Name
Neurexin-3
UniProt Synonym Protein Names
Neurexin III-alpha; Neurexin-3-alpha
Protein Family
UniProt Gene Name
NRXN3
UniProt Synonym Gene Names
C14orf60; KIAA0743
UniProt Entry Name
NRX3A_HUMAN
NCBI Protein Information
neurexin 3

NCBI Summary for NRXN3

This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]
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UniProt Comments for NRXN3

NRXN3: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. Belongs to the neurexin family. 7 isoforms of the human protein are produced by alternative promoter.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 14q31

Cellular Component: integral to plasma membrane; integral to membrane

Molecular Function: metal ion binding; calcium channel regulator activity; receptor activity; cell adhesion molecule binding

Biological Process: positive regulation of synaptogenesis; axon guidance; synaptic transmission; synaptogenesis; neurotransmitter secretion; adult behavior; neuron adhesion; learning; angiogenesis; social behavior
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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