Rabbit Anti-ABCC12 Polyclonal Antibody – Cat# MBS6270439

ABCC12 Antibody – Rabbit Polyclonal

Name: ABCC12 Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6270439
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6270439

MaxLight750 is a new Near IR stable dye conjugate comparable to DyLight750, Alexa Fluor700 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (759nm); Emission (780nm); Extinction Coefficient 240,000. More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ABCC12, Polyclonal Antibody

Full Product Name

ABCC12, ID (ABCC12, MRP9, Multidrug resistance-associated protein 9, ATP-binding cassette sub-family C member 12) (MaxLight 750)

Product Gene Name

anti-ABCC12 antibody

Product Synonym Names

ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

152,297 Da

Chromosome Location

Chromosome: 16; NC_000016.9 (48116884..48180681, complement). Location: 16q12.1

OMIM

607041

3D Structure

ModBase 3D Structure for Q96J65

Immunogen

ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-751 amino acids from the Central region of human ABCC12.

Conjugate

MaxLight750

Note

Preservative Free

Product Categories/Family for anti-ABCC12 antibody

Antibodies; Multi Drug Resistance (MDR)

Applications Tested/Suitable for anti-ABCC12 antibody

Immunohistochemistry (IHC), FLISA, Western Blot (WB)

Application Notes for anti-ABCC12 antibody

IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-ABCC12 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Haimeur, A., et al. Curr. Drug Metab. 5(1):21-53(2004). Bera, T.K., et al. Proc. Natl. Acad. Sci. U.S.A. 99(10):6997-7002(2002). Yabuuchi, H., et al. Biochem. Biophys. Res. Commun. 288(4):933-939(2001). Tammur, J., et al. Gene 273(1):89-96(2001).

Other Notes

Small volumes of anti-ABCC12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABCC12 purchase

MBS6270439 is an antibody targeting ABCC12. Also known as ABCC12, ID (ABCC12, MRP9, Multidrug resistance-associated protein 9, ATP-binding cassette sub-family C member 12) (MaxLight 750). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ABCC12. It may not necessarily be applicable to this product.

NCBI GI #

89111135

NCBI GeneID

94160

NCBI Accession #

NP_150229.2

UniProt Primary Accession #

Q96J65

UniProt Secondary Accession #

Q49AL2; Q8TAF0; Q8TEY2

UniProt Related Accession #

Q96J65

GenBank Nucleotide #

NM_033226.2

NCBI Official Full Name

multidrug resistance-associated protein 9

NCBI Official Synonym Full Names

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

NCBI Official Symbol

ABCC12

NCBI Official Synonym Symbols

MRP9

UniProt Protein Name

Multidrug resistance-associated protein 9

UniProt Synonym Protein Names

ATP-binding cassette sub-family C member 12

Protein Family

ABC transporter C family

UniProt Gene Name

ABCC12

UniProt Synonym Gene Names

MRP9

UniProt Entry Name

MRP9_HUMAN

NCBI Protein Information

multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12; ATP-binding cassette transporter sub-family C member 12

NCBI Summary for ABCC12

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]

UniProt Comments for ABCC12

ABCC12: Probable transporter. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, ABC family; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: mitochondrion; integral to membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; ATP binding

Biological Process: metabolic process; transmembrane transport

Research Articles on ABCC12

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ABCC12 antibody

Products by Pathway	Pathway Diagram
ABC Transporters Pathway antibodies	ABC Transporters Pathway Diagram
ABC Transporters Pathway antibodies	ABC Transporters Pathway Diagram

Diseases associated with anti-ABCC12 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3 publications with ABCC12 and Neoplasms
Liver Diseases Antibodies	>2 publications with ABCC12 and Liver Diseases
Liver Neoplasms Antibodies	>1 publications with ABCC12 and Liver Neoplasms
Necrosis Antibodies	>1 publications with ABCC12 and Necrosis
Inflammation Antibodies	>1 publications with ABCC12 and Inflammation

Organs/Tissues associated with anti-ABCC12 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with ABCC12 and Liver
Testis Antibodies	>3 publications with ABCC12 and Testis
Brain Antibodies	>2 publications with ABCC12 and Brain