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CSGALNACT2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS627200

Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). It is required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. More details

$895 / 0.2 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CSGALNACT2, Polyclonal Antibody
Full Product Name
CSGALNACT2, ID (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2, Beta4GalNAcT-2, GalNAcT-2, Chondroitin Sulfate N-acetylgalactosaminyltransferase 2, CHGN2, GALNACT2, PRO0082)
Product Gene Name
anti-CSGALNACT2 antibody
Product Synonym Names
Anti -CSGALNACT2, ID (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2, Beta4GalNAcT-2, GalNAcT-2, Chondroitin Sulfate N-acetylgalactosaminyltransferase 2, CHGN2, GALNACT2, PRO0082)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human CSGALNACT2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
62,572 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (43633934..43680750). Location: 10q11.21
3D Structure
ModBase 3D Structure for Q8N6G5
Immunogen
Synthetic peptide selected from the Center region of human CSGALNACT2 (KLH).

Product Categories/Family for anti-CSGALNACT2 antibody

Antibodies; Abs to Hormones; Steroids
Applications Tested/Suitable for anti-CSGALNACT2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CSGALNACT2 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-CSGALNACT2 antibody

Western blot analysis of CSGALNACT2 Antibody (Center) in 293 cell line lysates (35ug/lane). CSGALNACT2 (arrow) was detected using the purified Pab.
Rabbit Anti-CSGALNACT2 Polyclonal Antibody – Cat# MBS627200

Immunohistochemistry (IHC) of anti-CSGALNACT2 antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CSGALNACT2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-CSGALNACT2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS627200

Flow Cytometry (FC/FACS) of anti-CSGALNACT2 antibody

CSGALNACT2 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-CSGALNACT2 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS627200

Other Notes

Small volumes of anti-CSGALNACT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSGALNACT2 purchase

MBS627200 is an antibody targeting CSGALNACT2. Also known as CSGALNACT2, ID (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2, Beta4GalNAcT-2, GalNAcT-2, Chondroitin Sulfate N-acetylgalactosaminyltransferase 2, CHGN2, GALNACT2, PRO0082). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CSGALNACT2. It may not necessarily be applicable to this product.

NCBI GI #
24429592
NCBI GeneID
55454
NCBI Accession #
NP_061060.3
UniProt Primary Accession #
Q8N6G5
UniProt Secondary Accession #
Q6MZJ5; Q6MZP6; Q8TCH4; Q9P1I6; B3KWL7
UniProt Related Accession #
Q8N6G5
GenBank Nucleotide #
NM_018590.3
NCBI Official Full Name
chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Official Synonym Full Names
chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Official Symbol
CSGALNACT2
NCBI Official Synonym Symbols
CHGN2; PRO0082; FLJ43310; GALNACT2; MGC40204; GALNACT-2; DKFZp686H13226
UniProt Protein Name
Chondroitin sulfate N-acetylgalactosaminyltransferase 2
UniProt Synonym Protein Names
Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2
Protein Family
Chondroitin sulfate N-acetylgalactosaminyltransferase
UniProt Gene Name
CSGALNACT2
UniProt Synonym Gene Names
CHGN2; GALNACT2
UniProt Entry Name
CGAT2_HUMAN
NCBI Protein Information
chondroitin sulfate N-acetylgalactosaminyltransferase 2; beta4GalNAcT-2; beta 4 GalNAcT-2; OTTHUMP00000019478; chondroitin sulfate GalNAcT-2; chondroitin beta1,4 N-acetylgalactosaminyltransferase 2; chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2

NCBI Summary for CSGALNACT2

This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Dec 2012]

UniProt Comments for CSGALNACT2

GALNACT2: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.174; Transferase

Chromosomal Location of Human Ortholog: 10q11.21

Cellular Component: Golgi membrane; membrane; integral to Golgi membrane

Molecular Function: metal ion binding; acetylgalactosaminyltransferase activity; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

Biological Process: chondroitin sulfate metabolic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; carbohydrate metabolic process; pathogenesis; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process
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Research Articles on CSGALNACT2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CSGALNACT2 antibody

 Products by Pathway  Pathway Diagram
 Glycosaminoglycan Biosynthesis - Chondroitin Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Chondroitin Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis - Chondroitin Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Chondroitin Sulfate Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram

Diseases associated with anti-CSGALNACT2 antibody

 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >1 publications with CSGALNACT2 and Vascular Diseases
 Immune System Diseases Antibodies  >1 publications with CSGALNACT2 and Immune System Diseases

Organs/Tissues associated with anti-CSGALNACT2 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >1 publications with CSGALNACT2 and Bone Marrow
 Blood Antibodies  >1 publications with CSGALNACT2 and Blood
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