• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CTSH Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS627232

The protein is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The protein, which belongs to the… More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CTSH, Polyclonal Antibody
Full Product Name
CTSH, NT (Cathepsin H, Cathepsin H Mini Chain, Cathepsin H Heavy Chain, Cathepsin H Light Chain, CPSB)
Product Gene Name
anti-CTSH antibody
Product Synonym Names
Anti -CTSH, NT (Cathepsin H, Cathepsin H Mini Chain, Cathepsin H Heavy Chain, Cathepsin H Light Chain, CPSB)
Clonality
Polyclonal
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Purified
Purified.
Specificity
Recognizes human CTSH.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, 11c7entrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
37,364 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (79214092..79237420, complement). Location: 15q25.1
3D Structure
ModBase 3D Structure for Q6IBC3
Immunogen
CTSH (AAH02479, 1-336aa) full-length human protein.

Product Categories/Family for anti-CTSH antibody

Antibodies; Abs to Cathepsin
Applications Tested/Suitable for anti-CTSH antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CTSH antibody
Suitable for use in Western Blot and Immunohistochemistry (paraffin).

Other Notes

Small volumes of anti-CTSH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CTSH purchase

MBS627232 is an antibody targeting CTSH. Also known as CTSH, NT (Cathepsin H, Cathepsin H Mini Chain, Cathepsin H Heavy Chain, Cathepsin H Light Chain, CPSB). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CTSH. It may not necessarily be applicable to this product.

NCBI GI #
48145879
NCBI GeneID
1512
UniProt Primary Accession #
Q6IBC3
UniProt Related Accession #
P09668; Q68D46; Q6IBC3; Q6LAF8; Q96NY6
NCBI Official Full Name
CTSH
NCBI Official Synonym Full Names
cathepsin H
NCBI Official Symbol
CTSH
NCBI Official Synonym Symbols
CPSB; ACC-4; ACC-5; MGC1519; minichain; DKFZp686B24257
UniProt Protein Name
CTSH protein
Protein Family
Pro-cathepsin
UniProt Gene Name
CTSH
UniProt Entry Name
Q6IBC3_HUMAN
NCBI Protein Information
pro-cathepsin H; aleurain; cathepsin B3; cathepsin BA; OTTHUMP00000185564; N-benzoylarginine-beta-naphthylamide hydrolase

NCBI Summary for CTSH

The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. [provided by RefSeq]
Show more

UniProt Comments for CTSH

CTSH: Important for the overall degradation of proteins in lysosomes. Belongs to the peptidase C1 family.

Protein type: Protease; EC 3.4.22.16

Chromosomal Location of Human Ortholog: 15q25.1

Cellular Component: extracellular space; lysosome; acrosome; outer dense fiber; cytosol

Molecular Function: peptidase activity; protein binding; protein self-association; HLA-A specific activating MHC class I receptor activity; serine-type endopeptidase activity; cysteine-type endopeptidase activity; endopeptidase activity; protein complex binding; caspase activator activity; kininogen binding; aminopeptidase activity; cysteine-type peptidase activity

Biological Process: caspase activation; adaptive immune response; response to retinoic acid; protein destabilization; membrane protein proteolysis; proteolysis; antigen processing and presentation; positive regulation of angiogenesis; positive regulation of cell proliferation; zymogen activation; spermatogenesis; metanephros development; surfactant homeostasis; immune response-regulating signal transduction; T cell mediated cytotoxicity; negative regulation of apoptosis; positive regulation of cell migration
Show more

Research Articles on CTSH

1. CTSH overexpression in a subset hepatoma may be thyroid hormone receptor dependent and suggests that this overexpression has an important role in hepatoma progression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CTSH antibody

 Reference Product  PubMed Publications
 CSTB antibody  >7 publications with CTSH and CSTB
 CSTA antibody  >7 publications with CTSH and CSTA

Pathways associated with anti-CTSH antibody

 Products by Pathway  Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram

Diseases associated with anti-CTSH antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >58 publications with CTSH and Neoplasms
 Carcinoma Antibodies  >23 publications with CTSH and Carcinoma
 Nervous System Diseases Antibodies  >22 publications with CTSH and Nervous System Diseases
 Thyroid Diseases Antibodies  >16 publications with CTSH and Thyroid Diseases
 Inflammation Antibodies  >14 publications with CTSH and Inflammation
 Neoplasms, Experimental Antibodies  >13 publications with CTSH and Neoplasms, Experimental
 Lung Diseases Antibodies  >11 publications with CTSH and Lung Diseases
 Male Urogenital Diseases Antibodies  >10 publications with CTSH and Male Urogenital Diseases
 Adenocarcinoma Antibodies  >9 publications with CTSH and Adenocarcinoma
 Neuroectodermal Tumors Antibodies  >8 publications with CTSH and Neuroectodermal Tumors

Organs/Tissues associated with anti-CTSH antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >66 publications with CTSH and Blood
 Liver Antibodies  >55 publications with CTSH and Liver
 Kidney Antibodies  >34 publications with CTSH and Kidney
 Thyroid Antibodies  >29 publications with CTSH and Thyroid
 Muscle Antibodies  >25 publications with CTSH and Muscle
 Lung Antibodies  >24 publications with CTSH and Lung
 Brain Antibodies  >20 publications with CTSH and Brain
 Skin Antibodies  >18 publications with CTSH and Skin
 Spleen Antibodies  >14 publications with CTSH and Spleen
 Bone Antibodies  >11 publications with CTSH and Bone
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000