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LUC7-Like (LUC7L) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS627233

MBS627233 is an antibody targeting LUC7L. Also known as LUC7-like, CT (LUC7L, Luc7, hLuc7B1, LUC7B1, LUC7L1, FLJ10231, Putative RNA-binding Protein Luc7-like 1, Putative SR Protein LUC7B1, SR+89). Reactive in Human. Host: Rabbit. LUC7L may bind to RNA via its… More details

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Product Overview

Online Datasheet in PDF
Product Name
LUC7-like (LUC7L), Polyclonal Antibody
Full Product Name
LUC7-like, CT (LUC7L, Luc7, hLuc7B1, LUC7B1, LUC7L1, FLJ10231, Putative RNA-binding Protein Luc7-like 1, Putative SR Protein LUC7B1, SR+89)
Product Gene Name
anti-LUC7L antibody
Product Synonym Names
Anti -LUC7-like, CT (LUC7L, Luc7, hLuc7B1, LUC7B1, LUC7L1, FLJ10231, Putative RNA-binding Protein Luc7-like 1, Putative SR Protein LUC7B1, SR+89)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human LUC7L.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
38,405 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (238970..279449, complement). Location: 16p13.3
3D Structure
ModBase 3D Structure for Q1W6G4
Immunogen
Synthetic peptide selected from the C-terminal region of human LUC7L (KLH).

Product Categories/Family for anti-LUC7L antibody

Antibodies; Abs to RNA Binding Proteins
Applications Tested/Suitable for anti-LUC7L antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-LUC7L antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-LUC7L antibody

Western blot analysis of LUC7L Antibody (C-term) in K562 cell line lysates (35ug/lane). LUC7L (arrow) was detected using the purified Pab.
Rabbit Anti-LUC7L Polyclonal Antibody – Cat# MBS627233

Western Blot (WB) of anti-LUC7L antibody

Western blot analysis of LUC7L (arrow) using rabbit polyclonal LUC7L Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LUC7L gene (Lane 2) .
Rabbit Anti-LUC7L Polyclonal Antibody, Western Blot (WB) – Cat# MBS627233

Immunohistochemistry (IHC) of anti-LUC7L antibody

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with LUC7L Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-LUC7L Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS627233

Flow Cytometry (FC/FACS) of anti-LUC7L antibody

Flow cytometric analysis of K562 cells using LUC7L Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-LUC7L Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS627233

Other Notes

Small volumes of anti-LUC7L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LUC7L. It may not necessarily be applicable to this product.

NCBI GI #
13112037
NCBI GeneID
55692
UniProt Primary Accession #
Q1W6G4
UniProt Related Accession #
Q1W6G4; Q53G47; Q9NQ29
NCBI Official Full Name
LUC7-like (S. cerevisiae)
NCBI Official Synonym Full Names
LUC7-like (S. cerevisiae)
NCBI Official Symbol
LUC7L
NCBI Official Synonym Symbols
Luc7; SR+89; LUC7B1; hLuc7B1; FLJ10231; LUC7-LIKE
UniProt Protein Name
LUC7-like (S. cerevisiae)
Protein Family
Putative RNA-binding protein
UniProt Gene Name
LUC7L
UniProt Entry Name
Q1W6G4_HUMAN
NCBI Protein Information
putative RNA-binding protein Luc7-like 1; OTTHUMP00000067165; OTTHUMP00000067166; OTTHUMP00000067167; OTTHUMP00000194916; putative SR protein LUC7B1; sarcoplasmic reticulum protein LUC7B1

NCBI Summary for LUC7L

The LUC7L gene may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection (Tufarelli et al., 2001 [PubMed 11170747]).[supplied by OMIM]

UniProt Comments for LUC7L

LUC7L iso2: May bind to RNA via its Arg/Ser-rich domain. Belongs to the Luc7 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: snRNP U1

Molecular Function: mRNA binding; identical protein binding; RS domain binding; protein binding

Biological Process: mRNA splice site selection; negative regulation of striated muscle development
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Research Articles on LUC7L

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-LUC7L antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with LUC7L and Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with LUC7L and Neoplasm Metastasis
 Death Antibodies  >1 publications with LUC7L and Death

Organs/Tissues associated with anti-LUC7L antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with LUC7L and Muscle
 Adrenal Gland Antibodies  >1 publications with LUC7L and Adrenal Gland
 Lung Antibodies  >1 publications with LUC7L and Lung
 Embryonic Tissue Antibodies  >1 publications with LUC7L and Embryonic Tissue
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