Rabbit Anti-AP3S1 Polyclonal Antibody – Cat# MBS6274133

AP3S1 Antibody – Rabbit Polyclonal

Name: AP3S1 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6274133
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6274133

Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AP3S1, Polyclonal Antibody

Full Product Name

AP3S1, NT (AP3S1, CLAPS3, AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, Adapter-related protein complex 3 sigma-1 subunit, Clathrin-associated/assembly/adapter protein, small 3, Sigma-3A-adaptin, Sigma-adaptin 3a) (MaxLight 550)

Product Gene Name

anti-AP3S1 antibody

Product Synonym Names

AP3S1; CLAPS3; AP-3 complex subunit sigma-1; AP-3 complex subunit sigma-3A; Adapter-related protein complex 3 sigma-1 subunit; Clathrin-associated/assembly/adapter protein; small 3; Sigma-3A-adaptin; Sigma-adaptin 3a

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

21,732 Da

OMIM

601507

3D Structure

ModBase 3D Structure for Q92572

Immunogen

AP3S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human AP3S1.

Conjugate

MaxLight550

Note

Preservative Free

Product Categories/Family for anti-AP3S1 antibody

Antibodies; Clathrin

Applications Tested/Suitable for anti-AP3S1 antibody

Immunohistochemistry (IHC), FLISA, Western Blot (WB)

Application Notes for anti-AP3S1 antibody

IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-AP3S1 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Zhou, J.B., et al. Med. Sci. Monit. 16 (6), BR179-BR183 (2010): Lefrancois, S., et al. Dev. Cell 7(4):619-625(2004). Salazar, G., et al. Mol. Biol. Cell 15(2):575-587(2004). Nie, Z., et al. Dev. Cell 5(3):513-521(2003).

Other Notes

Small volumes of anti-AP3S1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AP3S1 purchase

MBS6274133 is an antibody targeting AP3S1. Also known as AP3S1, NT (AP3S1, CLAPS3, AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, Adapter-related protein complex 3 sigma-1 subunit, Clathrin-associated/assembly/adapter protein, small 3, Sigma-3A-adaptin, Sigma-adaptin 3a) (MaxLight 550). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AP3S1. It may not necessarily be applicable to this product.

NCBI GI #

4502861

NCBI GeneID

1176

NCBI Accession #

NP_001275.1

UniProt Primary Accession #

Q92572

UniProt Secondary Accession #

O00647; O00676; O00721; O00727; Q53XL4; Q6ICQ2

UniProt Related Accession #

Q92572

GenBank Nucleotide #

NM_001284.2

NCBI Official Full Name

AP-3 complex subunit sigma-1

NCBI Official Synonym Full Names

adaptor-related protein complex 3, sigma 1 subunit

NCBI Official Symbol

AP3S1

NCBI Official Synonym Symbols

CLAPS3; Sigma3A

UniProt Protein Name

AP-3 complex subunit sigma-1

UniProt Synonym Protein Names

AP-3 complex subunit sigma-3A; Adaptor-related protein complex 3 subunit sigma-1; Clathrin-associated/assembly/adaptor protein, small 3; Sigma-3A-adaptin; Sigma3A-adaptin; Sigma-adaptin 3a

Protein Family

AP-3 complex

UniProt Gene Name

AP3S1

UniProt Synonym Gene Names

CLAPS3; Sigma3A-adaptin

UniProt Entry Name

AP3S1_HUMAN

NCBI Protein Information

AP-3 complex subunit sigma-1; AP-3 complex sigma-3A subunit; AP-3 complex subunit sigma-3A; adapter-related protein complex 3 sigma-1 subunit; adapter-related protein complex 3 subunit sigma-1; adaptor-related protein complex 3 subunit sigma-1; clathrin-a

UniProt Comments for AP3S1

AP3S1: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes small subunit family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5q22

Cellular Component: Golgi apparatus; transport vesicle; cytoplasmic vesicle membrane; AP-type membrane coat adaptor complex

Molecular Function: protein binding; transporter activity; protein transporter activity

Biological Process: intracellular protein transport; anterograde synaptic vesicle transport; insulin receptor signaling pathway; anterograde axon cargo transport

Research Articles on AP3S1

1. KCNQ and AP3S1, but not MAN2A1 or ALDH7A1 have a role in risk of type 2 diabetes in the Chinese Northern Han population

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AP3S1 antibody

Reference Product	PubMed Publications
AP3M1 antibody	>1 publications with AP3S1 and AP3M1
AP3D1 antibody	>1 publications with AP3S1 and AP3D1

Pathways associated with anti-AP3S1 antibody

Products by Pathway	Pathway Diagram
Clathrin Derived Vesicle Budding Pathway antibodies	Clathrin Derived Vesicle Budding Pathway Diagram
Golgi Associated Vesicle Biogenesis Pathway antibodies	Golgi Associated Vesicle Biogenesis Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Trans-Golgi Network Vesicle Budding Pathway antibodies	Trans-Golgi Network Vesicle Budding Pathway Diagram

Diseases associated with anti-AP3S1 antibody

Disease Name	Pubmed Publications
Uterine Cervical Neoplasms Antibodies	>1 publications with AP3S1 and Uterine Cervical Neoplasms

Organs/Tissues associated with anti-AP3S1 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with AP3S1 and Muscle
Liver Antibodies	>1 publications with AP3S1 and Liver
Cervix Antibodies	>1 publications with AP3S1 and Cervix
Brain Antibodies	>1 publications with AP3S1 and Brain