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APOBEC3D Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6274443

MBS6274443 is an antibody targeting APOBEC3D. Also known as APOBEC3D, NT (APOBEC3D, Probable DNA dC->dU-editing enzyme APOBEC-3D) (MaxLight 750). Reactive in Human. Host: Rabbit. Unknown. Unable to reduce HIV-1 infectivity in vitro. More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APOBEC3D, Polyclonal Antibody
Full Product Name
APOBEC3D, NT (APOBEC3D, Probable DNA dC->dU-editing enzyme APOBEC-3D) (MaxLight 750)
Product Gene Name
Product Synonym Names
APOBEC3D; Probable DNA dC->dU-editing enzyme APOBEC-3D
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
46,598 Da
OMIM
AL022318 Genomic DNA
3D Structure
ModBase 3D Structure for Q96AK3
Immunogen
APOBEC3D antibody is generated from rabbits immunized with a KLH conjugated synthetic between 45-72 amino acids selected from the N-terminal region of human APOBEC3D.
Conjugate
MaxLight750
Note
Preservative Free
Applications Tested/Suitable for anti-APOBEC3D antibody
Western Blot (WB), FLISA
Application Notes for anti-APOBEC3D antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-APOBEC3D antibody

Zhang, W., et al. PLoS ONE 3 (12), E3963 (2008): Dang, Y., et al. J. Virol. 80(21):10522-10533(2006). Stenglein, M.D., et al. J. Biol. Chem. 281(25):16837-16841(2006). Conticello, S.G., et al. Mol. Biol. Evol. 22(2):367-377(2005). Harris, R.S., et al. Nat. Rev. Immunol. 4(11):868-877(2004).

Other Notes

Small volumes of anti-APOBEC3D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for APOBEC3D. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA dC->dU-editing enzyme APOBEC-3D
NCBI Official Synonym Full Names
apolipoprotein B mRNA editing enzyme catalytic subunit 3D
NCBI Official Symbol
APOBEC3D
NCBI Official Synonym Symbols
A3D; ARP6; APOBEC3E; APOBEC3DE
UniProt Protein Name
DNA dC->dU-editing enzyme APOBEC-3D
UniProt Gene Name
APOBEC3D
UniProt Synonym Gene Names
A3D
NCBI Protein Information
DNA dC->dU-editing enzyme APOBEC-3D

NCBI Summary for APOBEC3D

This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008]
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UniProt Comments for APOBEC3D

APOBEC3D: Probable DNA cytidine deaminase involved in foreign DNA clearance. May provide cellular innate resistance to a specific panel of genetic invaders including endogenous retroelements and a subset of viruses. Belongs to the cytidine and deoxycytidylate deaminase family.

Protein type: EC 3.5.4.-; Hydrolase

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cytoplasm

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; zinc ion binding

Biological Process: defense response to virus; innate immune response; negative regulation of retroviral genome replication
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-APOBEC3D antibody

 Organ/Tissue Name  Pubmed Publications
 Thymus Antibodies  >1 publications with APOBEC3D and Thymus
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