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ARG1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6274789

catalyzes the hydrolysis of arginine to ornithine and urea in arginine metabolism; regulates nitric oxide production [RGD]. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Arg1, Polyclonal Antibody
Full Product Name
Arg1, CT (Arg1, Arginase-1, Liver-type arginase, Type I arginase) (FITC)
Product Gene Name
anti-Arg1 antibody
Product Synonym Names
Arg1; Arginase-1; Liver-type arginase; Type I arginase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
34,973 Da
3D Structure
ModBase 3D Structure for P07824
Immunogen
Rat Arg1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-318 amino acids from the C-terminal region of human Rat Arg1.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-Arg1 antibody

Antibodies; Enzymes
Applications Tested/Suitable for anti-Arg1 antibody
Western Blot (WB), FLISA
Application Notes for anti-Arg1 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-Arg1 antibody

Rat Arg1 Antibody (C-term) western blot analysis in rat liver tissue lysates (35ug/lane).This demonstrates the Rat Arg1 antibody detected the Rat Arg1 protein (arrow).
Rabbit Anti-ARG1 Polyclonal Antibody – Cat# MBS6274789

Product References and Citations for anti-Arg1 antibody

Warnken, M., et al. Naunyn Schmiedebergs Arch. Pharmacol. 381(4):297-304(2010). Zhu, W., et al. Am. J. Physiol., Cell Physiol. 298 (4), C952-C960 (2010): Bagnost, T., et al. Hypertens. Res. 32(12):1130-1135(2009). Kim, J.H., et al. J. Appl. Physiol. 107(4):1249-1257(2009). Deng, K., et al. J. Neurosci. 29(30):9545-9552(2009).

Other Notes

Small volumes of anti-Arg1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Arg1 purchase

MBS6274789 is an antibody targeting Arg1. Also known as Arg1, CT (Arg1, Arginase-1, Liver-type arginase, Type I arginase) (FITC). Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Arg1. It may not necessarily be applicable to this product.

NCBI GI #
166091458
NCBI GeneID
29221
NCBI Accession #
NP_058830.2
UniProt Primary Accession #
P07824
UniProt Secondary Accession #
Q5BK93
UniProt Related Accession #
P07824
GenBank Nucleotide #
NM_017134.3
NCBI Official Full Name
arginase-1
NCBI Official Synonym Full Names
arginase 1
NCBI Official Symbol
Arg1
UniProt Protein Name
Arginase-1
UniProt Synonym Protein Names
Liver-type arginase; Type I arginase
Protein Family
Arginase
UniProt Gene Name
Arg1
UniProt Entry Name
ARGI1_RAT
NCBI Protein Information
arginase-1

NCBI Summary for Arg1

catalyzes the hydrolysis of arginine to ornithine and urea in arginine metabolism; regulates nitric oxide production [RGD, Feb 2006]

UniProt Comments for Arg1

ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.5.3.1; Amino Acid Metabolism - arginine and proline

Cellular Component: extracellular space; mitochondrial outer membrane; neuron projection; cell soma; cytoplasm; nucleus

Molecular Function: manganese ion binding; arginase activity

Biological Process: mammary gland involution; response to peptide hormone stimulus; maternal process involved in pregnancy; response to lipopolysaccharide; female pregnancy; response to vitamin A; response to selenium ion; response to vitamin E; response to methylmercury; response to wounding; response to axon injury; collagen biosynthetic process; aging; response to drug; response to herbicide; liver development; response to amino acid stimulus; response to manganese ion; response to cadmium ion; arginine metabolic process; response to zinc ion; response to steroid hormone stimulus; arginine catabolic process to ornithine; positive regulation of endothelial cell proliferation; lung development; response to amine stimulus; urea cycle
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Research Articles on Arg1

1. Intermittent hypoxia increases expression levels of arginase I and II proteins in adult rats.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Arg1 antibody

 Reference Product  PubMed Publications
 Nos2 antibody  >75 publications with Arg1 and Nos2
 Nos3 antibody  >14 publications with Arg1 and Nos3
 Asl antibody  >7 publications with Arg1 and Asl
 Nos1 antibody  >6 publications with Arg1 and Nos1
 Oat antibody  >6 publications with Arg1 and Oat
 Otc antibody  >6 publications with Arg1 and Otc

Pathways associated with anti-Arg1 antibody

 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine Biosynthesis Pathway antibodies  Arginine Biosynthesis Pathway Diagram
 Arginine Biosynthesis Pathway antibodies  Arginine Biosynthesis Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-Arg1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >160 publications with Arg1 and Inflammation
 Disease Models, Animal Antibodies  >90 publications with Arg1 and Disease Models, Animal
 Lung Diseases Antibodies  >68 publications with Arg1 and Lung Diseases
 Nervous System Diseases Antibodies  >65 publications with Arg1 and Nervous System Diseases
 Necrosis Antibodies  >50 publications with Arg1 and Necrosis
 Immune System Diseases Antibodies  >49 publications with Arg1 and Immune System Diseases
 Cardiovascular Diseases Antibodies  >47 publications with Arg1 and Cardiovascular Diseases
 Asthma Antibodies  >31 publications with Arg1 and Asthma
 Fibrosis Antibodies  >31 publications with Arg1 and Fibrosis
 Liver Diseases Antibodies  >27 publications with Arg1 and Liver Diseases

Organs/Tissues associated with anti-Arg1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >102 publications with Arg1 and Lung
 Brain Antibodies  >100 publications with Arg1 and Brain
 Liver Antibodies  >77 publications with Arg1 and Liver
 Small Intestine Antibodies  >41 publications with Arg1 and Small Intestine
 Spleen Antibodies  >33 publications with Arg1 and Spleen
 Eye Antibodies  >27 publications with Arg1 and Eye
 Colon Antibodies  >23 publications with Arg1 and Colon
 Connective Tissue Antibodies  >9 publications with Arg1 and Connective Tissue
 Pancreas Antibodies  >8 publications with Arg1 and Pancreas
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