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ASB3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6275545

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASB3, Polyclonal Antibody
Full Product Name
ASB3, NT (ASB3, Ankyrin repeat and SOCS box protein 3) (AP)
Product Gene Name
anti-ASB3 antibody
Product Synonym Names
ASB3; Ankyrin repeat and SOCS box protein 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
605760
3D Structure
ModBase 3D Structure for Q9Y575
Immunogen
ASB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human ASB3.
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-ASB3 antibody

Antibodies; Ankyrin
Applications Tested/Suitable for anti-ASB3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ASB3 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ASB3 antibody

Western blot analysis of ASB3 Antibody (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in A549 cell line lysate. ASB3 Antibody (N-term) (arrow) was detected using the purified Pab.
Rabbit Anti-ASB3 Polyclonal Antibody – Cat# MBS6275545

Western Blot (WB) of anti-ASB3 antibody

Western blot analysis of ASB3 Antibody (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse spleen tissue lysate. ASB3 Antibody (N-term) (arrow) was detected using the purified Pab.
Rabbit Anti-ASB3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6275545

Product References and Citations for anti-ASB3 antibody

Yang, Q., et al. BMC Med. Genet. 8 SUPPL 1, S12 (2007): Chung, A.S., et al. Mol. Cell. Biol. 25(11):4716-4726(2005). Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002). Kile, B.T., et al. Mol. Cell. Biol. 21(18):6189-6197(2001). Kile, B.T., et al. Gene 258 (1-2), 31-41 (2000).

Other Notes

Small volumes of anti-ASB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASB3 purchase

MBS6275545 is an antibody targeting ASB3. Also known as ASB3, NT (ASB3, Ankyrin repeat and SOCS box protein 3) (AP). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASB3. It may not necessarily be applicable to this product.

NCBI GI #
22208951
NCBI GeneID
51130
NCBI Accession #
NP_665862.1
NCBI Related Accession #
NP_057199.1
UniProt Primary Accession #
Q9Y575
UniProt Related Accession #
Q9Y575
GenBank Nucleotide #
NP_665862.1
NCBI Official Full Name
ankyrin repeat and SOCS box protein 3 isoform b
NCBI Official Synonym Full Names
ankyrin repeat and SOCS box containing 3
NCBI Official Symbol
ASB3
NCBI Official Synonym Symbols
ASB-3
UniProt Protein Name
Ankyrin repeat and SOCS box protein 3
Protein Family
Ankyrin repeat and SOCS box protein
UniProt Gene Name
ASB3
UniProt Synonym Gene Names
ASB-3
UniProt Entry Name
ASB3_HUMAN
NCBI Protein Information
ankyrin repeat and SOCS box protein 3

NCBI Summary for ASB3

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2011]
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Research Articles on ASB3

1. ASB3 dysfunction resulted from gene mutations or down-regulated expression frequently exists in colorectal cancer and likely plays a key role in the pathogenesis and progression of colorectal cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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