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NPTX2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS627592

NPTX2 is likely to play a role in the modification of cellular properties that underlie long-term plasticity. It binds to agar matrix in a calcium-dependent manner. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NPTX2, Polyclonal Antibody
Full Product Name
NPTX2, CT (Neuronal Pentraxin-2, NP2, Neuronal Pentraxin II, NP-II)
Product Gene Name
Product Synonym Names
Anti -NPTX2, CT (Neuronal Pentraxin-2, NP2, Neuronal Pentraxin II, NP-II)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human NPTX2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
47,042 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (98246597..98259181). Location: 7q21.3-q22.1
OMIM
600750
3D Structure
ModBase 3D Structure for P47972
Immunogen
Synthetic peptide selected from the C-terminal region of human NPTX2 (KLH).

Product Categories/Family for anti-NPTX2 antibody

Applications Tested/Suitable for anti-NPTX2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NPTX2 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50

Western Blot (WB) of anti-NPTX2 antibody

Western blot analysis of NARP(Nptx2) (arrow) using rabbit polyclonal NARP(Nptx2) Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NARP(Nptx2) gene (Lane 2) (Origene Technologies).
Rabbit Anti-NPTX2 Polyclonal Antibody – Cat# MBS627592

Immunohistochemistry (IHC) of anti-NPTX2 antibody

Formalin-fixed and paraffin-embedded human testis tissue reacted with NARP(Nptx2) Antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-NPTX2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS627592

Other Notes

Small volumes of anti-NPTX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NPTX2 purchase

MBS627592 is an antibody targeting NPTX2. Also known as NPTX2, CT (Neuronal Pentraxin-2, NP2, Neuronal Pentraxin II, NP-II). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NPTX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuronal pentraxin-2
NCBI Official Synonym Full Names
neuronal pentraxin II
NCBI Official Symbol
NPTX2
NCBI Official Synonym Symbols
NP2; NARP; NP-II
UniProt Protein Name
Neuronal pentraxin-2
UniProt Synonym Protein Names
Neuronal pentraxin II
Protein Family
UniProt Gene Name
NPTX2
UniProt Entry Name
NPTX2_HUMAN
NCBI Protein Information
neuronal pentraxin-2; apexin; OTTHUMP00000205574; neuronal activity-regulated pentaxin

NCBI Summary for NPTX2

This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq]
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UniProt Comments for NPTX2

NPTX2: Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q21.3-q22.1

Cellular Component: extracellular region

Molecular Function: metal ion binding; carbohydrate binding

Biological Process: synaptic transmission
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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