PRKACA Antibody – Rabbit Polyclonal

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by the PRKACA gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.

Small volumes of anti-PRKACA/PRKACB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS628100 is an antibody targeting PRKACA/PRKACB. Also known as PRKACA/PRKACB, NT (cAMP-dependent Protein Kinase Catalytic Subunit alpha, PKA C-alpha, PKACA/cAMP-dependent Protein Kinase Catalytic Subunit beta, PKA C-beta). Reactive in Human, Mouse. Host: Rabbit.