Obestatin Antibody – Rabbit Polyclonal

Control of appetite involves a number of gastrointestinal hormones that belong to the ghrelin-motilin ligand family that either stimulate food intake and gastric emptying or inhibit these responses.

Recently, a new member of the ghrelin-motilin family was identified by using bioinformatic predictions about enzyme cleavage of the prepropeptide of ghrelin. The newly identified 23aa, ghrelin-associated peptide was named obestatin. Although both peptides originate from the same precursor prepropeptide, they have opposing physiological roles. Obestatin exerts anorexigenic effects by decreasing food intake, gastric emptying, jejunal motility, and weight gain by binding to GPR39 orphan receptor, while ghrelin exerts opposing orexigenic effects by binding to growth hormone secretagogue receptor.

Small volumes of anti-Obestatin antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS628330 is an antibody targeting Obestatin. Also known as Anti-Obestatin (Appetite-regulating Hormone, Growth Hormone Secretagogue, Growth Hormone-releasing Peptide, Motilin-related Peptide, Protein M46, Ghrelin, GHRL, MTLRP, UNQ524/PRO1066). Reactive in Human. Host: Rabbit.