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KRT13 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS628352

KRT13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of… More details

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Product Overview

Online Datasheet in PDF
Product Name
KRT13, Polyclonal Antibody
Full Product Name
KRT13, NT (Keratin, Type I Cytoskeletal 13, Cytokeratin-13, CK-13, Keratin-13, K13)
Product Gene Name
Product Synonym Names
Anti -KRT13, NT (Keratin, Type I Cytoskeletal 13, Cytokeratin-13, CK-13, Keratin-13, K13)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human KRT13.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
49,588 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (39657233..39661865, complement). Location: 17q12-q21.2
OMIM
148065
3D Structure
ModBase 3D Structure for P13646
Immunogen
Synthetic peptide selected from the N-terminal region of human KRT13 (KLH).
Applications Tested/Suitable for anti-KRT13 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-KRT13 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100

Western Blot (WB) of anti-KRT13 antibody

Western blot analysis of KRT13 antibody (N-term) in 293 cell line lysates (35ug/lane). KRT13 (arrow) was detected using the purified Pab.
Rabbit Anti-KRT13 Polyclonal Antibody – Cat# MBS628352

Immunohistochemistry (IHC) of anti-KRT13 antibody

KRT13 Antibody (N-term) (RB18903) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KRT13 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-KRT13 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS628352

Testing Data of anti-KRT13 antibody

KRT13 Antibody (N-term) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-KRT13 Polyclonal Antibody, Testing Data – Cat# MBS628352

Other Notes

Small volumes of anti-KRT13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KRT13 purchase

MBS628352 is an antibody targeting KRT13. Also known as KRT13, NT (Keratin, Type I Cytoskeletal 13, Cytokeratin-13, CK-13, Keratin-13, K13). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT13. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
keratin, type I cytoskeletal 13 isoform b
NCBI Official Synonym Full Names
keratin 13
NCBI Official Symbol
KRT13
NCBI Official Synonym Symbols
K13; CK13; MGC3781; MGC161462
UniProt Protein Name
Keratin, type I cytoskeletal 13
UniProt Synonym Protein Names
Cytokeratin-13; CK-13; Keratin-13
Protein Family
UniProt Gene Name
KRT13
UniProt Entry Name
K1C13_HUMAN
NCBI Protein Information
keratin, type I cytoskeletal 13; CK-13; keratin-13; cytokeratin 13; cytokeratin-13; OTTHUMP00000164632; OTTHUMP00000164633

NCBI Summary for KRT13

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq]
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UniProt Comments for KRT13

K13: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K4

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: intermediate filament cytoskeleton; keratin filament; nucleus

Molecular Function: structural molecule activity

Biological Process: response to radiation; tongue morphogenesis; cytoskeleton organization and biogenesis

Disease: White Sponge Nevus 2
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KRT13 antibody

 Reference Product  PubMed Publications
 KRT7 antibody  >1 publications with KRT13 and KRT7
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