• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

FASTK Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS628589

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1,… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FASTK, Polyclonal Antibody
Full Product Name
FASTK, CT (Fas-activated Serine/Threonine Kinase, FAST Kinase)
Product Gene Name
Product Synonym Names
Anti -FASTK, CT (Fas-activated Serine/Threonine Kinase, FAST Kinase)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human FASTK. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
51,504 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (150773708..150777951, complement). Location: 7q35
3D Structure
ModBase 3D Structure for Q9BWD7
Immunogen
Synthetic peptide selected from the C-terminal region of human FASTK (KLH).
Applications Tested/Suitable for anti-FASTK antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-FASTK antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-FASTK antibody

Western blot analysis of hFASTK-R534 in Jurkat cell line lysates (35ug/lane).FASTK (arrow) was detected using the purified Pab.
Rabbit Anti-FASTK Polyclonal Antibody – Cat# MBS628589

Western Blot (WB) of anti-FASTK antibody

Western blot analysis of hFASTK-R534 in mouse heart tissue lysates (35ug/lane).FASTK (arrow) was detected using the purified Pab.
Rabbit Anti-FASTK Polyclonal Antibody, Western Blot (WB) – Cat# MBS628589

Other Notes

Small volumes of anti-FASTK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FASTK purchase

MBS628589 is an antibody targeting FASTK. Also known as FASTK, CT (Fas-activated Serine/Threonine Kinase, FAST Kinase). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FASTK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
FASTK protein
NCBI Official Synonym Full Names
Fas-activated serine/threonine kinase
NCBI Official Symbol
FASTK
NCBI Official Synonym Symbols
FAST
UniProt Protein Name
FASTK protein
UniProt Gene Name
FASTK
UniProt Entry Name
Q9BWD7_HUMAN
NCBI Protein Information
fas-activated serine/threonine kinase; FAST kinase; OTTHUMP00000213278; OTTHUMP00000213305; OTTHUMP00000213306; OTTHUMP00000213307

NCBI Summary for FASTK

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq]
Show more

UniProt Comments for FASTK

FASTK: an atypical protein kinase. Fas-mediated apoptosis is characterized by FASTK- dephosphorylation and TIA-1-phosphorylation. Both are activated and FASTK-mediated TIA-1 activation play a key role in apoptosis.

Protein type: EC 2.7.11.8; Protein kinase, atypical; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); ATYPICAL group; FAST family

Chromosomal Location of Human Ortholog: 7q35

Cellular Component: mitochondrion

Molecular Function: protein serine/threonine kinase activity; protein binding; Fas-activated serine/threonine kinase activity; ATP binding

Biological Process: regulation of RNA splicing; protein amino acid phosphorylation
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000