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At-Rich Interactive Domain-Containing Protein 3b (ARID3B) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS628600

ARIDB3 is a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. This protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. Members… More details

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Product Overview

Online Datasheet in PDF
Product Name
AT-rich Interactive Domain-containing Protein 3B (ARID3B), Polyclonal Antibody
Full Product Name
AT-rich Interactive Domain-containing Protein 3B, CT (ARID3B, ARID Domain-containing Protein 3B, Bright-like Protein, Bright and Dead Ringer Protein, BDP, DRIL2)
Product Gene Name
anti-ARID3B antibody
Product Synonym Names
Anti -AT-rich Interactive Domain-containing Protein 3B, CT (ARID3B, ARID Domain-containing Protein 3B, Bright-like Protein, Bright and Dead Ringer Protein, BDP, DRIL2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human ARIDB3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
60,637 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (74833548..74890472). Location: 15q24
OMIM
612457
3D Structure
ModBase 3D Structure for Q8IVW6
Immunogen
Synthetic peptide selected from the C-terminal region of human ARIDB3 (KLH).

Product Categories/Family for anti-ARID3B antibody

Antibodies; Abs to Binding Proteins
Applications Tested/Suitable for anti-ARID3B antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ARID3B antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50

Western Blot (WB) of anti-ARID3B antibody

Western blot analysis of ARIDB3 Antibody (C-term) in K562 cell line lysates (35ug/lane). ARIDB3 (arrow) was detected using the purified Pab.
Rabbit Anti-ARID3B Polyclonal Antibody – Cat# MBS628600

Immunohistochemistry (IHC) of anti-ARID3B antibody

Formalin-fixed and paraffin-embedded human testis tissue reacted with ARIDB3 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-ARID3B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS628600

Other Notes

Small volumes of anti-ARID3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARID3B purchase

MBS628600 is an antibody targeting ARID3B. Also known as AT-rich Interactive Domain-containing Protein 3B, CT (ARID3B, ARID Domain-containing Protein 3B, Bright-like Protein, Bright and Dead Ringer Protein, BDP, DRIL2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARID3B. It may not necessarily be applicable to this product.

NCBI GI #
5453638
NCBI GeneID
10620
NCBI Accession #
NP_006456.1
UniProt Primary Accession #
Q8IVW6
UniProt Secondary Accession #
O95443; Q59HC9; Q6P9C9
UniProt Related Accession #
Q8IVW6
GenBank Nucleotide #
NM_006465.2
NCBI Official Full Name
AT-rich interactive domain-containing protein 3B
NCBI Official Synonym Full Names
AT rich interactive domain 3B (BRIGHT-like)
NCBI Official Symbol
ARID3B
NCBI Official Synonym Symbols
BDP; DRIL2
UniProt Protein Name
AT-rich interactive domain-containing protein 3B
UniProt Synonym Protein Names
Bright and dead ringer protein; Bright-like protein
Protein Family
AT-rich interactive domain-containing protein
UniProt Gene Name
ARID3B
UniProt Synonym Gene Names
BDP; DRIL2
UniProt Entry Name
ARI3B_HUMAN
NCBI Protein Information
AT-rich interactive domain-containing protein 3B; OTTHUMP00000180679; bright-like protein; bright and dead ringer protein; ARID domain-containing protein 3B; AT rich interactive domain 3B (BRIGHT- like)

NCBI Summary for ARID3B

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq]
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UniProt Comments for ARID3B

ARID3B: Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Tumor suppressor

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: nucleoplasm; nucleus

Molecular Function: DNA binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
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Research Articles on ARID3B

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ARID3B antibody

 Disease Name  Pubmed Publications
 Female Urogenital Diseases Antibodies  >1 publications with ARID3B and Female Urogenital Diseases
 Gonadal Disorders Antibodies  >1 publications with ARID3B and Gonadal Disorders
 Neurodegenerative Diseases Antibodies  >1 publications with ARID3B and Neurodegenerative Diseases

Organs/Tissues associated with anti-ARID3B antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with ARID3B and Blood
 Bone Antibodies  >1 publications with ARID3B and Bone
 Brain Antibodies  >1 publications with ARID3B and Brain
 Bone Marrow Antibodies  >1 publications with ARID3B and Bone Marrow
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