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CIAO1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6286101

CIAO1 is an essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. More details

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Product Overview

Online Datasheet in PDF
Product Name
CIAO1, Polyclonal Antibody
Full Product Name
CIAO1, ID (CIAO1, WDR39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39) (MaxLight 405)
Product Gene Name
Product Synonym Names
CIAO1; WDR39; Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
37,840 Da
OMIM
604333
3D Structure
ModBase 3D Structure for O76071
Immunogen
CIAO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CIAO1.
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-CIAO1 antibody

Applications Tested/Suitable for anti-CIAO1 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-CIAO1 antibody
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-CIAO1 antibody

Srinivasan, V., et al. Structure 15(10):1246-1257(2007). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006). Johnstone, R.W., et al. J. Biol. Chem. 273(18):10880-10887(1998).

Other Notes

Small volumes of anti-CIAO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CIAO1 purchase

MBS6286101 is an antibody targeting CIAO1. Also known as CIAO1, ID (CIAO1, WDR39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CIAO1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
probable cytosolic iron-sulfur protein assembly protein CIAO1
NCBI Official Synonym Full Names
cytosolic iron-sulfur assembly component 1
NCBI Official Symbol
CIAO1
NCBI Official Synonym Symbols
CIA1; WDR39
UniProt Protein Name
Probable cytosolic iron-sulfur protein assembly protein CIAO1
UniProt Synonym Protein Names
WD repeat-containing protein 39
UniProt Gene Name
CIAO1
UniProt Entry Name
CIAO1_HUMAN
NCBI Protein Information
probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat domain 39; WD repeat-containing protein 39; WD40 protein Ciao1; cytosolic iron-sulfur protein assembly 1 homolog

UniProt Comments for CIAO1

CIAO1: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. Belongs to the WD repeat CIA1 family.

Chromosomal Location of Human Ortholog: 2q11.2

Biological Process: regulation of transcription from RNA polymerase II promoter; iron-sulfur cluster assembly; positive regulation of cell proliferation; chromosome segregation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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