• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SERPINB3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS628628

SPB3 may act as a protease inhibitor to modulate the host immune response against tumor cells. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SERPINB3, Polyclonal Antibody
Full Product Name
SERPINB3, NT (Serpin B3, Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3, Squamous Cell Carcinoma Antigen 1, SCCA-1, Protein T4-A, SCCA1, SCCA, SPB3)
Product Gene Name
Product Synonym Names
Anti -SERPINB3, NT (Serpin B3, Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3, Squamous Cell Carcinoma Antigen 1, SCCA-1, Protein T4-A, SCCA1, SCCA, SPB3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human SERPINB3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
44,565 Da
Chromosome Location
Chromosome: 18; NC_000018.9 (61322431..61329197, complement). Location: 18q21.3
OMIM
600517
3D Structure
ModBase 3D Structure for P29508
Immunogen
Synthetic peptide corresponding to aa47-77 at the N-terminal region of human SERPINB3, conjugated to KLH.
Applications Tested/Suitable for anti-SERPINB3 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-SERPINB3 antibody
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry.
Dilution: ELISA: 1:1000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Flow Cytometry: 1:10-1:50

Western Blot (WB) of anti-SERPINB3 antibody

Western blot analysis of SPB3 antibody (N-term) in 293 cell line lysates (35ug/lane). SPB3 (arrow) was detected using the purified Pab.
Rabbit Anti-SERPINB3 Polyclonal Antibody – Cat# MBS628628

Immunohistochemistry (IHC) of anti-SERPINB3 antibody

SPB3 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SPB3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-SERPINB3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS628628

Flow Cytometry (FC/FACS) of anti-SERPINB3 antibody

SPB3 Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-SERPINB3 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS628628

Other Notes

Small volumes of anti-SERPINB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SERPINB3 purchase

MBS628628 is an antibody targeting SERPINB3. Also known as SERPINB3, NT (Serpin B3, Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3, Squamous Cell Carcinoma Antigen 1, SCCA-1, Protein T4-A, SCCA1, SCCA, SPB3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINB3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serpin B3
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade B (ovalbumin), member 3
NCBI Official Symbol
SERPINB3
NCBI Official Synonym Symbols
SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD
UniProt Protein Name
Serpin B3
UniProt Synonym Protein Names
Protein T4-A; Squamous cell carcinoma antigen 1
Protein Family
UniProt Gene Name
SERPINB3
UniProt Synonym Gene Names
SCCA; SCCA1
UniProt Entry Name
SPB3_HUMAN
NCBI Protein Information
serpin B3; protein T4-A; OTTHUMP00000066804; OTTHUMP00000066805; squamous cell carcinoma antigen 1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3

UniProt Comments for SERPINB3

SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: extracellular space; cytoplasm; cytoplasmic vesicle; nucleus; vesicle

Molecular Function: viral receptor activity; serine-type endopeptidase inhibitor activity; protease binding; cysteine protease inhibitor activity

Biological Process: negative regulation of proteolysis; negative regulation of JNK activity; entry of virus into host cell; positive regulation of cell proliferation; negative regulation of catalytic activity; negative regulation of peptidase activity; positive regulation of cell migration
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000