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CNDP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6287107

CNDP1 encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This protein contains trinucleotide (CTG) repeat length polymorphism… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CNDP1, Polyclonal Antibody
Full Product Name
CNDP1, CT (CNDP1, CN1, CPGL2, Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase) (PE)
Product Gene Name
Product Synonym Names
CNDP1; CN1; CPGL2; Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
56,706 Da
OMIM
609064
3D Structure
ModBase 3D Structure for Q96KN2
Immunogen
CNDP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422~451 amino acids from the C-terminal region of human CNDP1.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Applications Tested/Suitable for anti-CNDP1 antibody
Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-CNDP1 antibody
FC/FACS: 1:10-50
FLISA: 1:1,000
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-CNDP1 antibody

Western blot analysis of CNDP1 Antibody (C-term) in CEM cell line lysates (35ug/lane). CNDP1 (arrow) was detected using the purified Pab.
Rabbit Anti-CNDP1 Polyclonal Antibody – Cat# MBS6287107

Immunohistochemistry (IHC) of anti-CNDP1 antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with CNDP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-CNDP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6287107

Flow Cytometry (FC/FACS) of anti-CNDP1 antibody

CNDP1 Antibody (C-term) flow cytometry analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-CNDP1 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6287107

Product References and Citations for anti-CNDP1 antibody

Craig, D.W., et.al., Diabet. Med. 26 (11), 1090-1098 (2009). Mooyaart, A.L., et.al., Diabetes Res. Clin. Pract. 85 (3), 272-278 (2009).

Other Notes

Small volumes of anti-CNDP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CNDP1 purchase

MBS6287107 is an antibody targeting CNDP1. Also known as CNDP1, CT (CNDP1, CN1, CPGL2, Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CNDP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
carnosine dipeptidase 1 (metallopeptidase M20 family), isoform CRA_a
NCBI Official Synonym Full Names
carnosine dipeptidase 1 (metallopeptidase M20 family)
NCBI Official Symbol
CNDP1
NCBI Official Synonym Symbols
CN1; CPGL2; HsT2308
UniProt Protein Name
Beta-Ala-His dipeptidase
UniProt Synonym Protein Names
CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase
UniProt Gene Name
CNDP1
UniProt Synonym Gene Names
CN1; CPGL2
UniProt Entry Name
CNDP1_HUMAN
NCBI Protein Information
beta-Ala-His dipeptidase; carnosinase 1; serum carnosinase; CNDP dipeptidase 1; glutamate carboxypeptidase-like protein 2

NCBI Summary for CNDP1

This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]
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UniProt Comments for CNDP1

CNDP1: a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - histidine; Protease; Secreted, signal peptide; Secreted; Other Amino Acids Metabolism - beta-alanine; EC 3.4.13.20

Chromosomal Location of Human Ortholog: 18q22.3

Cellular Component: extracellular region

Molecular Function: dipeptidase activity; metallopeptidase activity; carboxypeptidase activity; metal ion binding

Biological Process: proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CNDP1 antibody

 Reference Product  PubMed Publications
 CARNS1 antibody  >1 publications with CNDP1 and CARNS1
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