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COL19A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6287616

This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
COL19A1, Polyclonal Antibody
Full Product Name
COL19A1, NT (COL19A1, Collagen alpha-1(XIX) chain, Collagen alpha-1(Y) chain) (Biotin)
Product Gene Name
anti-COL19A1 antibody
Product Synonym Names
COL19A1; Collagen alpha-1(XIX) chain; Collagen alpha-1(Y) chain
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
115,221 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (70576448..70922157). Location: 6q12-q13
OMIM
120165
3D Structure
ModBase 3D Structure for Q14993
Immunogen
COL19A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 174-204 amino acids selected from the N-terminal region of human COL19A1.
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-COL19A1 antibody

Antibodies; Collagen
Applications Tested/Suitable for anti-COL19A1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-COL19A1 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-COL19A1 antibody

COL19A1 Antibody (N-term) western blot analysis in Uterus tissue lysates (35ug/lane).This demonstrates the COL19A1 antibody detected the COL19A1 protein (arrow).
Rabbit Anti-COL19A1 Polyclonal Antibody – Cat# MBS6287616

Western Blot (WB) of anti-COL19A1 antibody

COL19A1 Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the COL19A1 antibody detected the COL19A1 protein (arrow).
Rabbit Anti-COL19A1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6287616

Product References and Citations for anti-COL19A1 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010): Boudko, S.P., et al. J. Biol. Chem. 283(49):34345-34351(2008). Kapyla, J., et al. J. Biol. Chem. 279(49):51677-51687(2004). Mungall, A.J., et al. Nature 425(6960):805-811(2003).

Other Notes

Small volumes of anti-COL19A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COL19A1 purchase

MBS6287616 is an antibody targeting COL19A1. Also known as COL19A1, NT (COL19A1, Collagen alpha-1(XIX) chain, Collagen alpha-1(Y) chain) (Biotin). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for COL19A1. It may not necessarily be applicable to this product.

NCBI GI #
47778921
NCBI GeneID
1310
NCBI Accession #
NP_001849.2
UniProt Primary Accession #
Q14993
UniProt Secondary Accession #
Q00559; Q05850; Q12885; Q13676; Q14DH1; Q5JUF0; Q5T424; Q9H572; Q9NPZ2; Q9NQP2
UniProt Related Accession #
Q14993
GenBank Nucleotide #
NM_001858.4
NCBI Official Full Name
collagen alpha-1(XIX) chain
NCBI Official Synonym Full Names
collagen, type XIX, alpha 1
NCBI Official Symbol
COL19A1
NCBI Official Synonym Symbols
COL9A1L; D6S228E
UniProt Protein Name
Collagen alpha-1(XIX) chain
UniProt Synonym Protein Names
Collagen alpha-1(Y) chain
UniProt Gene Name
COL19A1
UniProt Entry Name
COJA1_HUMAN
NCBI Protein Information
collagen alpha-1(XIX) chain; collagen alpha-1(XIX) chain; collagen alpha-1(Y) chain; collagen alpha 1 (Y) chain; a1 chain of type XIX collagen; collagen XIX, alpha-1 polypeptide

UniProt Comments for COL19A1

COL19A1: May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle. Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 6q12-q13

Cellular Component: proteinaceous extracellular matrix; collagen; endoplasmic reticulum lumen; extracellular region

Molecular Function: protein binding, bridging; extracellular matrix structural constituent

Biological Process: collagen catabolic process; extracellular matrix disassembly; cell-cell adhesion; skeletal muscle development; extracellular matrix organization and biogenesis; cell adhesion; cell differentiation; skeletal development
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Research Articles on COL19A1

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-COL19A1 antibody

 Products by Pathway  Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Degradation Of Collagen Pathway antibodies  Degradation Of Collagen Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram

Diseases associated with anti-COL19A1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with COL19A1 and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with COL19A1 and Brain Diseases

Organs/Tissues associated with anti-COL19A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >6 publications with COL19A1 and Muscle
 Brain Antibodies  >4 publications with COL19A1 and Brain
 Embryonic Tissue Antibodies  >2 publications with COL19A1 and Embryonic Tissue
 Eye Antibodies  >1 publications with COL19A1 and Eye
 Kidney Antibodies  >1 publications with COL19A1 and Kidney
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