Rabbit Anti-DSCR3 Polyclonal Antibody – Cat# MBS628945

Western blot analysis of DSCR3 Antibody (N-term) in Y79 cell line lysates (35ug/lane). DSCR3 (arrow) was detected using the purified Pab.

DSCR3 Antibody – Rabbit Polyclonal

Name: DSCR3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS628945
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS628945

The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome,… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DSCR3, Polyclonal Antibody

Full Product Name

DSCR3, NT (Down Syndrome Critical Region Protein 3, Down Syndrome Critical Region Protein A, DCRA, DSCRA)

Product Gene Name

anti-DSCR3 antibody

Product Synonym Names

Anti -DSCR3, NT (Down Syndrome Critical Region Protein 3, Down Syndrome Critical Region Protein A, DCRA, DSCRA)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human DSCR3.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

33,010 Da

Chromosome Location

Chromosome: 21; NC_000021.8 (38595726..38639833, complement). Location: 21q22.2

OMIM

605298

3D Structure

ModBase 3D Structure for O14972

Immunogen

Synthetic peptide selected from the N-terminal region of human DSCR3 (KLH).

Product Categories/Family for anti-DSCR3 antibody

Antibodies; Abs to Disease Markers

Applications Tested/Suitable for anti-DSCR3 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-DSCR3 antibody

Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100

Other Notes

Small volumes of anti-DSCR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DSCR3 purchase

MBS628945 is an antibody targeting DSCR3. Also known as DSCR3, NT (Down Syndrome Critical Region Protein 3, Down Syndrome Critical Region Protein A, DCRA, DSCRA). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DSCR3. It may not necessarily be applicable to this product.

NCBI GI #

5174425

NCBI GeneID

10311

NCBI Accession #

NP_006043.1

UniProt Primary Accession #

O14972

UniProt Secondary Accession #

Q2TAY6; B2R6T8; D3DSH4

UniProt Related Accession #

O14972; O60768

GenBank Nucleotide #

NM_006052.1

NCBI Official Full Name

Down syndrome critical region protein 3

NCBI Official Synonym Full Names

Down syndrome critical region gene 3

NCBI Official Symbol

DSCR3

NCBI Official Synonym Symbols

DCRA; DSCRA; MGC117385

UniProt Protein Name

Down syndrome critical region protein 3

UniProt Synonym Protein Names

Down syndrome critical region protein A

Protein Family

Down syndrome critical region protein

UniProt Gene Name

DSCR3

UniProt Synonym Gene Names

DCRA; DSCRA

UniProt Entry Name

DSCR3_HUMAN

NCBI Protein Information

Down syndrome critical region protein 3; OTTHUMP00000109095; OTTHUMP00000109096; OTTHUMP00000109098; Down syndrome critical region protein A

UniProt Comments for DSCR3

DSCR3: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: nucleus; endosome

Molecular Function: protein transporter activity

Biological Process: intracellular protein transport

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-DSCR3 antibody

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>7 publications with DSCR3 and Congenital Abnormalities
Neurobehavioral Manifestations Antibodies	>6 publications with DSCR3 and Neurobehavioral Manifestations

Organs/Tissues associated with anti-DSCR3 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with DSCR3 and Blood
Brain Antibodies	>3 publications with DSCR3 and Brain
Heart Antibodies	>1 publications with DSCR3 and Heart
Vascular Antibodies	>1 publications with DSCR3 and Vascular
Liver Antibodies	>1 publications with DSCR3 and Liver
Muscle Antibodies	>1 publications with DSCR3 and Muscle
Lung Antibodies	>1 publications with DSCR3 and Lung
Kidney Antibodies	>1 publications with DSCR3 and Kidney