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SOD3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS628951

SOD3 is a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. This protein is thought to protect the brain, lungs, and other tissues… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SOD3, Polyclonal Antibody
Full Product Name
SOD3, NT (Extracellular Superoxide Dismutase [Cu-Zn], EC-SOD)
Product Gene Name
Product Synonym Names
Anti -SOD3, NT (Extracellular Superoxide Dismutase [Cu-Zn], EC-SOD)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human SOD3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,851 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (24797085..24802467). Location: 4p15.3-p15.1
OMIM
185490
3D Structure
ModBase 3D Structure for P08294
Immunogen
Synthetic peptide selected from the N-terminal region of human SOD3 (KLH).
Applications Tested/Suitable for anti-SOD3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SOD3 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100

Western Blot (WB) of anti-SOD3 antibody

Western blot analysis of SOD3 Antibody (N-term) in K562 cell line lysates (35ug/lane). SOD3 (arrow) was detected using the purified Pab.
Rabbit Anti-SOD3 Polyclonal Antibody – Cat# MBS628951

Immunohistochemistry (IHC) of anti-SOD3 antibody

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with SOD3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-SOD3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS628951

Flow Cytometry (FC/FACS) of anti-SOD3 antibody

Flow cytometric analysis of K562 cells using SOD3 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-SOD3 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS628951

Other Notes

Small volumes of anti-SOD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SOD3 purchase

MBS628951 is an antibody targeting SOD3. Also known as SOD3, NT (Extracellular Superoxide Dismutase [Cu-Zn], EC-SOD). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SOD3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
SOD3
NCBI Official Synonym Full Names
superoxide dismutase 3, extracellular
NCBI Official Symbol
SOD3
NCBI Official Synonym Symbols
EC-SOD; MGC20077
UniProt Protein Name
Extracellular superoxide dismutase [Cu-Zn]
UniProt Gene Name
SOD3
UniProt Entry Name
SODE_HUMAN
NCBI Protein Information
extracellular superoxide dismutase [Cu-Zn]; extracellular superoxide dismutase [Cu-Zn]; OTTHUMP00000158715

NCBI Summary for SOD3

This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq]
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UniProt Comments for SOD3

SOD3: Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. Belongs to the Cu-Zn superoxide dismutase family.

Protein type: Secreted; Oxidoreductase; Secreted, signal peptide; EC 1.15.1.1

Chromosomal Location of Human Ortholog: 4p15.2

Cellular Component: extracellular matrix; extracellular space; Golgi lumen; cytoplasm; extracellular region; trans-Golgi network; nucleus

Molecular Function: heparin binding; protein binding; copper ion binding; zinc ion binding; superoxide dismutase activity

Biological Process: response to reactive oxygen species; removal of superoxide radicals; response to copper ion; response to hypoxia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SOD3 antibody

 Reference Product  PubMed Publications
 FBLN5 antibody  >1 publications with SOD3 and FBLN5
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