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IL17RB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS629070

IL17RB is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. More details

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Product Overview

Online Datasheet in PDF
Product Name
IL17RB, Polyclonal Antibody
Full Product Name
IL17RB, ID (Interleukin-17 Receptor B, IL-17 Receptor B, IL-17RB, Interleukin-17B Receptor, IL-17B Receptor, IL-17 Receptor Homolog 1, IL-17Rh1, IL17Rh1, Cytokine Receptor-like 4, CRL4,UNQ2501/PRO19612, IL17BR, EVI27, IL17RB)
Product Gene Name
Product Synonym Names
Anti -IL17RB, ID (Interleukin-17 Receptor B, IL-17 Receptor B, IL-17RB, Interleukin-17B Receptor, IL-17B Receptor, IL-17 Receptor Homolog 1, IL-17Rh1, IL17Rh1, Cytokine Receptor-like 4, CRL4,UNQ2501/PRO19612, IL17BR, EVI27, IL17RB)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human IL17RB.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
55,885 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (53880577..53899827). Location: 3p21.1
OMIM
605458
3D Structure
ModBase 3D Structure for Q9NRM6
Immunogen
Synthetic peptide selected from the Center region of human IL17RB (KLH).

Product Categories/Family for anti-IL17RB antibody

Applications Tested/Suitable for anti-IL17RB antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-IL17RB antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100

Western Blot (WB) of anti-IL17RB antibody

Western blot analysis of IL17RB Antibody (Center) in MDA-MB468 cell line lysates (35ug/lane). IL17RB (arrow) was detected using the purified Pab.
Rabbit Anti-IL17RB Polyclonal Antibody – Cat# MBS629070

Immunohistochemistry (IHC) of anti-IL17RB antibody

Formalin-fixed and paraffin-embedded human colon carcinoma reacted with IL17RB Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-IL17RB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS629070

Flow Cytometry (FC/FACS) of anti-IL17RB antibody

Flow cytometric analysis of HepG2 cells using IL17RB Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-IL17RB Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS629070

Other Notes

Small volumes of anti-IL17RB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL17RB purchase

MBS629070 is an antibody targeting IL17RB. Also known as IL17RB, ID (Interleukin-17 Receptor B, IL-17 Receptor B, IL-17RB, Interleukin-17B Receptor, IL-17B Receptor, IL-17 Receptor Homolog 1, IL-17Rh1, IL17Rh1, Cytokine Receptor-like 4, CRL4,UNQ2501/PRO19612, IL17BR, EVI27, IL17RB). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL17RB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-17 receptor B
NCBI Official Synonym Full Names
interleukin 17 receptor B
NCBI Official Symbol
IL17RB
NCBI Official Synonym Symbols
CRL4; EVI27; IL17BR; IL17RH1; MGC5245
UniProt Protein Name
Interleukin-17 receptor B
UniProt Synonym Protein Names
Cytokine receptor-like 4; IL-17 receptor homolog 1; IL-17Rh1; IL17Rh1; Interleukin-17B receptor
UniProt Gene Name
IL17RB
UniProt Synonym Gene Names
CRL4; EVI27; IL17BR
UniProt Entry Name
I17RB_HUMAN
NCBI Protein Information
interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; OTTHUMP00000212736; OTTHUMP00000212737; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1

NCBI Summary for IL17RB

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq]
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UniProt Comments for IL17RB

IL17RB: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: cell surface; membrane; integral to plasma membrane; cytoplasm; extracellular region

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-17 receptor activity

Biological Process: cytokine and chemokine mediated signaling pathway; defense response; regulation of cell growth
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL17RB antibody

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