Rabbit Anti-DOC2A Polyclonal Antibody – Cat# MBS6293178

DOC2A Antibody – Rabbit Polyclonal

Name: DOC2A Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6293178
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6293178

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DOC2A, Polyclonal Antibody

Full Product Name

DOC2A, ID (DOC2A, Double C2-like domain-containing protein alpha) (MaxLight 750)

Product Gene Name

anti-DOC2A antibody

Product Synonym Names

DOC2A; Double C2-like domain-containing protein alpha

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

18,384 Da

OMIM

604567

3D Structure

ModBase 3D Structure for Q14183

Immunogen

DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-314 amino acids from the Central region of human DOC2A.

Conjugate

MaxLight750

Note

Preservative Free

Product Categories/Family for anti-DOC2A antibody

Antibodies; Proteins

Applications Tested/Suitable for anti-DOC2A antibody

Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)

Application Notes for anti-DOC2A antibody

FC/FACS: 1:10-50
FLISA: 1:1,000
IHC: 1:10-50
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-DOC2A antibody

Shimada, M., et al. Hum. Genet. 128(4):433-441(2010). Glessner, J.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(23):10584-10589(2010). Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009). Kumar, R.A., et al. PLoS ONE 4 (2), E4582 (2009): Higashio, H., et al. J. Immunol. 180(7):4774-4784(2008).

Other Notes

Small volumes of anti-DOC2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DOC2A purchase

MBS6293178 is an antibody targeting DOC2A. Also known as DOC2A, ID (DOC2A, Double C2-like domain-containing protein alpha) (MaxLight 750). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DOC2A. It may not necessarily be applicable to this product.

NCBI GI #

47078261

NCBI GeneID

8448

NCBI Accession #

NP_003577.2

UniProt Primary Accession #

Q14183

UniProt Secondary Accession #

Q6P4G4; Q7Z5G0; Q8IVX0; B4DEJ2; H3BNH6

UniProt Related Accession #

Q14183

GenBank Nucleotide #

NM_003586.2

NCBI Official Full Name

double C2-like domain-containing protein alpha

NCBI Official Synonym Full Names

double C2 domain alpha

NCBI Official Symbol

DOC2A

NCBI Official Synonym Symbols

Doc2

UniProt Protein Name

Double C2-like domain-containing protein alpha

Protein Family

Double C2-like domain-containing protein

UniProt Gene Name

DOC2A

UniProt Synonym Gene Names

Doc2; Doc2-alpha

UniProt Entry Name

DOC2A_HUMAN

NCBI Protein Information

double C2-like domain-containing protein alpha

NCBI Summary for DOC2A

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Research Articles on DOC2A

1. Study analyzed Doc2alpha and Doc2beta and found that Doc2 responds to changes in [Ca2+], with markedly slower kinetics as compared to the cytosolic domain of syt I (syt), and operates on a timescale consistent with asynchronous neurotransmitter release.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DOC2A antibody

Reference Product	PubMed Publications
UNC13B antibody	>6 publications with DOC2A and UNC13B
SEZ6L2 antibody	>1 publications with DOC2A and SEZ6L2
DYNLT1 antibody	>1 publications with DOC2A and DYNLT1

Diseases associated with anti-DOC2A antibody

Disease Name	Pubmed Publications
Seizures Antibodies	>1 publications with DOC2A and Seizures
Brain Diseases Antibodies	>1 publications with DOC2A and Brain Diseases
Bone Diseases Antibodies	>1 publications with DOC2A and Bone Diseases
Fibrosis Antibodies	>1 publications with DOC2A and Fibrosis
Nervous System Diseases Antibodies	>1 publications with DOC2A and Nervous System Diseases

Organs/Tissues associated with anti-DOC2A antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>18 publications with DOC2A and Brain
Bone Antibodies	>2 publications with DOC2A and Bone
Blood Antibodies	>2 publications with DOC2A and Blood
Muscle Antibodies	>1 publications with DOC2A and Muscle
Embryonic Tissue Antibodies	>1 publications with DOC2A and Embryonic Tissue
Lung Antibodies	>1 publications with DOC2A and Lung