DUSP13 Antibody – Rabbit Polyclonal

Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined.

Kim, S.J., et al. Proteins 66(1):239-245(2007). Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006). Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005). Chen, H.H., et al. J. Biol. Chem. 279(40):41404-41413(2004). Deloukas, P., et al. Nature 429(6990):375-381(2004).

Small volumes of anti-DUSP13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS6293791 is an antibody targeting DUSP13. Also known as DUSP13, CT (DUSP13, BEDP, MDSP, Dual specificity protein phosphatase 13 isoform MDSP, Branching-enzyme interacting DSP, Muscle-restricted DSP) (MaxLight 490). Reactive in Human. Host: Rabbit.