Sheep Anti-HSD17B3 Polyclonal Antibody – Cat# MBS629415

Testosterone, 17alpha (HSD17B3) Antibody – Sheep Polyclonal

Name: HSD17B3 Antibody; Polyclonal; Sheep; MyBioSource
Brand: MyBioSource
SKU: MBS629415
Price: 940 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS629415

MBS629415 is an antibody targeting Hsd17b3. Also known as Testosterone, 17alpha. Host: Sheep. More details

$940 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Testosterone, 17alpha (Hsd17b3), Polyclonal Antibody

Full Product Name

Testosterone, 17alpha

Product Gene Name

anti-Hsd17b3 antibody

Product Synonym Names

Anti -Testosterone, 17alpha

Clonality

Polyclonal

Host

Sheep

Form/Format

Supplied as a liquid in PBS, pH 7.2, containing 0.09% sodium azide.

Purity/Purification

Purified
Purified

Specificity

Recognizes 17 alpha -Testosterone.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

34,330 Da

Chromosome Location

Chromosome: 13; NC_000079.6 (64058274..64089201, complement). Location: 13 B3; 13

3D Structure

ModBase 3D Structure for P70385

Immunogen

17alpha Testosterone(3)-BTG

Product Categories/Family for anti-Hsd17b3 antibody

Antibodies; Abs to Hormones; Steroids

Applications Tested/Suitable for anti-Hsd17b3 antibody

ELISA (EL/EIA)

Application Notes for anti-Hsd17b3 antibody

Suitable for use in ELISA., , Recommended Dilution:, ELISA: 2.5ug/ml, Optimal dilutions to be determined by the researcher.

Other Notes

Small volumes of anti-Hsd17b3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Hsd17b3. It may not necessarily be applicable to this product.

NCBI GI #

153792573

NCBI GeneID

15487

NCBI Accession #

NP_032317.2

UniProt Primary Accession #

P70385

UniProt Secondary Accession #

G3UWF9

UniProt Related Accession #

P70385

GenBank Nucleotide #

NM_008291.3

NCBI Official Full Name

testosterone 17-beta-dehydrogenase 3

NCBI Official Synonym Full Names

hydroxysteroid (17-beta) dehydrogenase 3

NCBI Official Symbol

Hsd17b3

UniProt Protein Name

Testosterone 17-beta-dehydrogenase 3

UniProt Synonym Protein Names

17-beta-hydroxysteroid dehydrogenase type 3; 17-beta-HSD 3; Testicular 17-beta-hydroxysteroid dehydrogenase

Protein Family

Testosterone 17-beta-dehydrogenase

UniProt Gene Name

Hsd17b3

UniProt Synonym Gene Names

Edh17b3; 17-beta-HSD 3

UniProt Entry Name

DHB3_MOUSE

NCBI Protein Information

testosterone 17-beta-dehydrogenase 3; 17-beta-HSD 3; 17(beta)HSD type 3; 17-beta-hydroxysteroid dehydrogenase type 3; testicular 17-beta-hydroxysteroid dehydrogenase

UniProt Comments for Hsd17b3

HSD17B3: Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH. Defects in HSD17B3 are the cause of male pseudohermaphrodism with gynecomastia (MPH). These individuals have unambiguous female external genitalia at birth, but fail to menstruate at the time of expected puberty and instead virilize as evidenced by growth of the phallus. Breast development may or may not take place. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.

Protein type: EC 1.1.1.64; Lipid Metabolism - androgen and estrogen; Oxidoreductase

Cellular Component: intracellular membrane-bound organelle

Molecular Function: estradiol 17-beta-dehydrogenase activity; testosterone 17-beta-dehydrogenase (NADP+) activity; oxidoreductase activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity

Biological Process: metabolic process; lipid metabolic process; steroid biosynthetic process

Research Articles on Hsd17b3

1. Enzyme activities of 3-betaHSDH increase as the sound pressure levels increase in adrenal cortex zona fasciculate polygonal cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Hsd17b3 antibody

Reference Product	PubMed Publications
Cyp19a1 antibody	>12 publications with Hsd17b3 and Cyp19a1
Srd5a2 antibody	>11 publications with Hsd17b3 and Srd5a2
Hsd3b1 antibody	>9 publications with Hsd17b3 and Hsd3b1
Srd5a1 antibody	>7 publications with Hsd17b3 and Srd5a1
Cyp11b2 antibody	>4 publications with Hsd17b3 and Cyp11b2
Hsd3b2 antibody	>4 publications with Hsd17b3 and Hsd3b2
Hsd3b6 antibody	>4 publications with Hsd17b3 and Hsd3b6

Pathways associated with anti-Hsd17b3 antibody

Products by Pathway	Pathway Diagram
Steroid Biosynthesis Pathway antibodies	Steroid Biosynthesis Pathway Diagram
Steroid Hormone Biosynthesis Pathway antibodies	Steroid Hormone Biosynthesis Pathway Diagram
Steroid Hormone Biosynthesis Pathway antibodies	Steroid Hormone Biosynthesis Pathway Diagram
Biosynthesis Of Androgens Pathway antibodies	Biosynthesis Of Androgens Pathway Diagram

Diseases associated with anti-Hsd17b3 antibody

Disease Name	Pubmed Publications
Urogenital Abnormalities Antibodies	>17 publications with Hsd17b3 and Urogenital Abnormalities
Disorders of Sex Development Antibodies	>16 publications with Hsd17b3 and Disorders of Sex Development
Genital Diseases, Male Antibodies	>14 publications with Hsd17b3 and Genital Diseases, Male
Prostatic Diseases Antibodies	>9 publications with Hsd17b3 and Prostatic Diseases
Prostatic Neoplasms Antibodies	>9 publications with Hsd17b3 and Prostatic Neoplasms
Hypospadias Antibodies	>5 publications with Hsd17b3 and Hypospadias
Ovarian Diseases Antibodies	>3 publications with Hsd17b3 and Ovarian Diseases
Hyperplasia Antibodies	>2 publications with Hsd17b3 and Hyperplasia
Prenatal Exposure Delayed Effects Antibodies	>2 publications with Hsd17b3 and Prenatal Exposure Delayed Effects
Infertility, Male Antibodies	>2 publications with Hsd17b3 and Infertility, Male

Organs/Tissues associated with anti-Hsd17b3 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>20 publications with Hsd17b3 and Testis
Uncharacterized Tissue Antibodies	>1 publications with Hsd17b3 and Uncharacterized Tissue