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Secretogranin II Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS629468

Chromogranin-C is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Secretogranin II, Polyclonal Antibody
Full Product Name
Secretogranin II, ID (Secretogranin-2, Chromogranin-C, SgII, Secretoneurin, SN, CHGC, SCG2)
Product Synonym Names
Anti -Secretogranin II, ID (Secretogranin-2, Chromogranin-C, SgII, Secretoneurin, SN, CHGC, SCG2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.40% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human Chromogranin-C.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide selected from the Center region of human Chromogranin-C (KLH).
Applications Tested/Suitable for anti-Secretogranin II antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-Secretogranin II antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100

Western Blot (WB) of anti-Secretogranin II antibody

Western blot analysis of hromogranin-C Antibody (Center) in Ramos cell line lysates (35ug/lane). SCG2 (arrow) was detected using the purified Pab.
Rabbit Anti-Secretogranin II Polyclonal Antibody – Cat# MBS629468

Immunohistochemistry (IHC) of anti-Secretogranin II antibody

Chromogranin-C Antibody (Center) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Chromogranin-C Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-Secretogranin II Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS629468

Other Notes

Small volumes of anti-Secretogranin II antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Secretogranin II purchase

MBS629468 is an antibody targeting Secretogranin II. Also known as Secretogranin II, ID (Secretogranin-2, Chromogranin-C, SgII, Secretoneurin, SN, CHGC, SCG2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Secretogranin II. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Official Full Name
secretogranin II
Protein Family

UniProt Comments for Secretogranin II

SCG2: Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. Belongs to the chromogranin/secretogranin protein family.

Protein type: Cytokine; Secreted; Secreted, signal peptide; Apoptosis; Cell cycle regulation; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q35-q36

Cellular Component: extracellular space; secretory granule

Molecular Function: cytokine activity; chemoattractant activity

Biological Process: positive chemotaxis; negative regulation of endothelial cell proliferation; MAPKKK cascade; eosinophil chemotaxis; protein secretion; endothelial cell migration; positive regulation of endothelial cell proliferation; angiogenesis; inflammatory response; induction of positive chemotaxis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Secretogranin II antibody

 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with Secretogranin II and FLNA
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