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ELOVL5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6295410

MBS6295410 is an antibody targeting ELOVL5. Also known as ELOVL5, CT (ELOVL5, ELOVL2, Elongation of very long chain fatty acids protein 5, 3-keto acyl-CoA synthase ELOVL5, ELOVL fatty acid elongase 5, Fatty acid elongase 1) (MaxLight 650). Reactive in Human.… More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ELOVL5, Polyclonal Antibody
Full Product Name
ELOVL5, CT (ELOVL5, ELOVL2, Elongation of very long chain fatty acids protein 5, 3-keto acyl-CoA synthase ELOVL5, ELOVL fatty acid elongase 5, Fatty acid elongase 1) (MaxLight 650)
Product Gene Name
anti-ELOVL5 antibody
Product Synonym Names
ELOVL5; ELOVL2; Elongation of very long chain fatty acids protein 5; 3-keto acyl-CoA synthase ELOVL5; ELOVL fatty acid elongase 5; Fatty acid elongase 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
35,293 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (53132196..53213977, complement). Location: 6p21.1-p12.1
OMIM
611805
3D Structure
ModBase 3D Structure for Q9NYP7
Immunogen
ELOVL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270~299 amino acids from the C-terminal region of human ELOVL5.
Conjugate
MaxLight650
Note
Preservative Free

Product Categories/Family for anti-ELOVL5 antibody

Antibodies; Enzymes; Synthase
Applications Tested/Suitable for anti-ELOVL5 antibody
Flow Cytometry (FC/FACS), FLISA, Western Blot (WB)
Application Notes for anti-ELOVL5 antibody
FC/FACS: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-ELOVL5 antibody

Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008). Olsen, J.V., et al. Cell 127(3):635-648(2006). Barragan, I., et al. Int. J. Mol. Med. 16(6):1163-1167(2005).

Other Notes

Small volumes of anti-ELOVL5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ELOVL5. It may not necessarily be applicable to this product.

NCBI GI #
338827646
NCBI GeneID
60481
NCBI Accession #
NP_001229757.1
UniProt Primary Accession #
Q9NYP7
UniProt Secondary Accession #
Q59EL3; Q5TGH5; Q6NXE7; Q7L2S5; Q8NCG4; Q9UI22; B4DZJ2; F6SH78
UniProt Related Accession #
Q9NYP7
GenBank Nucleotide #
NM_001242828.1
NCBI Official Full Name
elongation of very long chain fatty acids protein 5 isoform 2
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 5
NCBI Official Symbol
ELOVL5
NCBI Official Synonym Symbols
HELO1; dJ483K16.1; RP3-483K16.1
UniProt Protein Name
Elongation of very long chain fatty acids protein 5
UniProt Synonym Protein Names
3-keto acyl-CoA synthase ELOVL5; ELOVL fatty acid elongase 5; ELOVL FA elongase 5; Fatty acid elongase 1; hELO1; Very-long-chain 3-oxoacyl-CoA synthase 5
UniProt Gene Name
ELOVL5
UniProt Synonym Gene Names
ELOVL2; ELOVL FA elongase 5; hELO1
UniProt Entry Name
ELOV5_HUMAN
NCBI Protein Information
elongation of very long chain fatty acids protein 5; ELOVL FA elongase 5; fatty acid elongase 1; 3-keto acyl-CoA synthase ELOVL5; very-long-chain 3-oxoacyl-CoA synthase 5; homolog of yeast long chain polyunsaturated fatty acid elongatio; homolog of yeast

NCBI Summary for ELOVL5

ELOVL5 plays a role in elongation of long-chain polyunsaturated fatty acids (Leonard et al., 2000 [PubMed 10970790]).[supplied by OMIM, Mar 2008]

UniProt Comments for ELOVL5

ELOVL5: Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. Belongs to the ELO family.

Protein type: Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 2.3.1.199; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: endoplasmic reticulum membrane; membrane; cell soma; endoplasmic reticulum; dendrite; integral to membrane

Molecular Function: protein binding; fatty acid elongase activity

Biological Process: unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process; linoleic acid metabolic process; unsaturated fatty acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process

Disease: Spinocerebellar Ataxia 38
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Research Articles on ELOVL5

1. a novel link between Elovl5-mediated synthesis of 18:1,n-7 and GNG through the control of the mTORC2-Akt-FoxO1 pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ELOVL5 antibody

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acyl-CoA Biosynthesis Pathway antibodies  Fatty Acyl-CoA Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Linoleic Acid (LA) Metabolism Pathway antibodies  Linoleic Acid (LA) Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-ELOVL5 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >23 publications with ELOVL5 and Fatty Liver
 Liver Diseases Antibodies  >5 publications with ELOVL5 and Liver Diseases
 Neoplasms Antibodies  >3 publications with ELOVL5 and Neoplasms
 Prostatic Neoplasms Antibodies  >2 publications with ELOVL5 and Prostatic Neoplasms
 Inflammation Antibodies  >2 publications with ELOVL5 and Inflammation
 Prostatic Diseases Antibodies  >2 publications with ELOVL5 and Prostatic Diseases
 Hepatomegaly Antibodies  >1 publications with ELOVL5 and Hepatomegaly
 Heart Diseases Antibodies  >1 publications with ELOVL5 and Heart Diseases
 Liver Neoplasms Antibodies  >1 publications with ELOVL5 and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >1 publications with ELOVL5 and Cardiovascular Diseases
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