• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LLGL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS629626

LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LLGL1, Polyclonal Antibody
Full Product Name
LLGL1, NT (Lethal(2) Giant Larvae Protein Homolog 1, LLGL, Human Homolog To The D-lgl Gene Protein, Hugl-1, DLG4, DLG4, HUGL, HUGL1)
Product Gene Name
anti-LLGL1 antibody
Product Synonym Names
Anti -LLGL1, NT (Lethal(2) Giant Larvae Protein Homolog 1, LLGL, Human Homolog To The D-lgl Gene Protein, Hugl-1, DLG4, DLG4, HUGL, HUGL1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human LLGL1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
115,418 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (18128936..18148189). Location: 17p11.2
OMIM
600966
3D Structure
ModBase 3D Structure for Q15334
Immunogen
Synthetic peptide selected from the N-terminal region of human LLGL1 (KLH).

Product Categories/Family for anti-LLGL1 antibody

Antibodies; Abs to Proteins
Applications Tested/Suitable for anti-LLGL1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-LLGL1 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-LLGL1 antibody

Western blot analysis of anti-hLLGL1 Pab in 293 cell line lysate. hLLGL1(arrow) was detected using the purified Pab.
Rabbit Anti-LLGL1 Polyclonal Antibody – Cat# MBS629626

Other Notes

Small volumes of anti-LLGL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LLGL1 purchase

MBS629626 is an antibody targeting LLGL1. Also known as LLGL1, NT (Lethal(2) Giant Larvae Protein Homolog 1, LLGL, Human Homolog To The D-lgl Gene Protein, Hugl-1, DLG4, DLG4, HUGL, HUGL1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LLGL1. It may not necessarily be applicable to this product.

NCBI GI #
62020859
NCBI GeneID
3996
UniProt Primary Accession #
Q15334
UniProt Secondary Accession #
O00188; Q58F11; Q86UK6; A7MBM7
UniProt Related Accession #
Q15334
NCBI Official Full Name
LLGL1 protein
NCBI Official Synonym Full Names
lethal giant larvae homolog 1 (Drosophila)
NCBI Official Symbol
LLGL1
NCBI Official Synonym Symbols
DLG4; HUGL; LLGL; HUGL1; HUGL-1
UniProt Protein Name
Lethal(2) giant larvae protein homolog 1
UniProt Synonym Protein Names
DLG4; Hugl-1; Human homolog to the D-lgl gene protein
Protein Family
Lethal(2) giant larvae protein
UniProt Gene Name
LLGL1
UniProt Synonym Gene Names
DLG4; HUGL; HUGL1
UniProt Entry Name
L2GL1_HUMAN
NCBI Protein Information
lethal(2) giant larvae protein homolog 1; lethal(2) giant larvae protein homolog 1; OTTHUMP00000065700; human homolog to the D-lgl gene protein

NCBI Summary for LLGL1

This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq]
Show more

UniProt Comments for LLGL1

LLGL1: Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Belongs to the WD repeat L(2)GL family.

Protein type: Motility/polarity/chemotaxis; Cell adhesion; Cytoskeletal

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: Golgi membrane; cortical actin cytoskeleton; cytoskeleton; axon; early endosome membrane; cytoplasm; Golgi cis cisterna; trans-Golgi network membrane

Molecular Function: protein binding; structural molecule activity; protein kinase binding

Biological Process: Golgi to plasma membrane transport; exocytosis; axonogenesis; protein complex assembly; cortical actin cytoskeleton organization and biogenesis; maintenance of apical/basal cell polarity
Show more

Research Articles on LLGL1

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LLGL1 antibody

 Reference Product  PubMed Publications
 ACD antibody  >1 publications with LLGL1 and ACD

Pathways associated with anti-LLGL1 antibody

 Products by Pathway  Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram

Diseases associated with anti-LLGL1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with LLGL1 and Neoplasms
 Kidney Diseases Antibodies  >2 publications with LLGL1 and Kidney Diseases
 Neoplasm Metastasis Antibodies  >2 publications with LLGL1 and Neoplasm Metastasis
 Carcinoma, Renal Cell Antibodies  >2 publications with LLGL1 and Carcinoma, Renal Cell
 Kidney Neoplasms Antibodies  >2 publications with LLGL1 and Kidney Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with LLGL1 and Liver Neoplasms, Experimental
 Adenoma Antibodies  >1 publications with LLGL1 and Adenoma
 Carcinoma, Hepatocellular Antibodies  >1 publications with LLGL1 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >1 publications with LLGL1 and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with LLGL1 and Liver Neoplasms

Organs/Tissues associated with anti-LLGL1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >4 publications with LLGL1 and Kidney
 Embryonic Tissue Antibodies  >3 publications with LLGL1 and Embryonic Tissue
 Brain Antibodies  >3 publications with LLGL1 and Brain
 Lymph Node Antibodies  >2 publications with LLGL1 and Lymph Node
 Lung Antibodies  >1 publications with LLGL1 and Lung
 Heart Antibodies  >1 publications with LLGL1 and Heart
 Intestine Antibodies  >1 publications with LLGL1 and Intestine
 Eye Antibodies  >1 publications with LLGL1 and Eye
 Uncharacterized Tissue Antibodies  >1 publications with LLGL1 and Uncharacterized Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000