Rabbit Anti-FGD3 Polyclonal Antibody – Cat# MBS6298925

FGD3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the FGD3 antibody detected the FGD3 protein (arrow).

FGD3 Antibody – Rabbit Polyclonal

Name: FGD3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6298925
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6298925

FGD3 promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity). More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FGD3, Polyclonal Antibody

Full Product Name

FGD3, CT (FGD3, ZFYVE5, FYVE, RhoGEF and PH domain-containing protein 3, Zinc finger FYVE domain-containing protein 5) (Biotin)

Product Gene Name

anti-FGD3 antibody

Product Synonym Names

FGD3; ZFYVE5; FYVE; RhoGEF and PH domain-containing protein 3; Zinc finger FYVE domain-containing protein 5

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

79,273 Da

3D Structure

ModBase 3D Structure for Q5JSP0

Immunogen

FGD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 574-601 amino acids from the C-terminal region of human FGD3.

Conjugate

Biotin

Note

Preservative Free

Product Categories/Family for anti-FGD3 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

Applications Tested/Suitable for anti-FGD3 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-FGD3 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-FGD3 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Delague, V., et al. Am. J. Hum. Genet. 81(1):1-16(2007). Humphray, S.J., et al. Nature 429(6990):369-374(2004). Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003): Salehi, A.H., et al. J. Biol. Chem. 277(50):48043-48050(2002).

Other Notes

Small volumes of anti-FGD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGD3 purchase

MBS6298925 is an antibody targeting FGD3. Also known as FGD3, CT (FGD3, ZFYVE5, FYVE, RhoGEF and PH domain-containing protein 3, Zinc finger FYVE domain-containing protein 5) (Biotin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FGD3. It may not necessarily be applicable to this product.

NCBI GI #

134133248

NCBI GeneID

89846

NCBI Accession #

NP_001077005.1

UniProt Primary Accession #

Q5JSP0

UniProt Secondary Accession #

Q4VX84; Q7Z7D9; Q8N5G1; F8W7P2

UniProt Related Accession #

Q5JSP0

GenBank Nucleotide #

NM_001083536.1

NCBI Official Full Name

FYVE, RhoGEF and PH domain-containing protein 3 isoform a

NCBI Official Synonym Full Names

FYVE, RhoGEF and PH domain containing 3

NCBI Official Symbol

FGD3

NCBI Official Synonym Symbols

ZFYVE5

UniProt Protein Name

FYVE, RhoGEF and PH domain-containing protein 3

UniProt Synonym Protein Names

Zinc finger FYVE domain-containing protein 5

Protein Family

FYVE, RhoGEF and PH domain-containing protein

UniProt Gene Name

FGD3

UniProt Synonym Gene Names

ZFYVE5

UniProt Entry Name

FGD3_HUMAN

NCBI Protein Information

FYVE, RhoGEF and PH domain-containing protein 3

Research Articles on FGD3

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-FGD3 antibody

Products by Pathway	Pathway Diagram
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies	Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
G Alpha (12/13) Signalling Events Pathway antibodies	G Alpha (12/13) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
NRAGE Signals Death Through JNK Pathway antibodies	NRAGE Signals Death Through JNK Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Rho GTPase Cycle Pathway antibodies	Rho GTPase Cycle Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram
Signaling By Rho GTPases Pathway antibodies	Signaling By Rho GTPases Pathway Diagram

Diseases associated with anti-FGD3 antibody

Disease Name	Pubmed Publications
Chromosome Aberrations Antibodies	>2 publications with FGD3 and Chromosome Aberrations
Urogenital Abnormalities Antibodies	>1 publications with FGD3 and Urogenital Abnormalities
Abnormalities, Multiple Antibodies	>1 publications with FGD3 and Abnormalities, Multiple
Breast Neoplasms Antibodies	>1 publications with FGD3 and Breast Neoplasms
Weight Loss Antibodies	>1 publications with FGD3 and Weight Loss

Organs/Tissues associated with anti-FGD3 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>2 publications with FGD3 and Bone
Lymph Node Antibodies	>1 publications with FGD3 and Lymph Node
Eye Antibodies	>1 publications with FGD3 and Eye
Lymph Antibodies	>1 publications with FGD3 and Lymph