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Opioid Receptor, Delta, Aa360-372 (OPRD1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS629914

The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In… More details

$680 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Opioid Receptor, delta, aa360-372 (OPRD1), Polyclonal Antibody
Full Product Name
Opioid Receptor, delta, CT, aa360-372
Product Gene Name
anti-OPRD1 antibody
Product Synonym Names
Anti -Opioid Receptor, delta, CT, aa360-372
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Supplied as a lyophilized powder. Reconstitute with 100ul sterile, 40-50% glycerol, PBS, 10mg/ml BSA.
Purity/Purification
Serum
Serum.
Specificity
Shown to be specific for the C-terminal of the delta opioid receptor. Recognizes Delta Opioid Receptor (aa360-372) 100%; Delta Opioid Receptor
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol, PBS, 10mg/ml BSA., aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
40,369 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (29138654..29190208). Location: 1p36.1-p34.3
OMIM
165195
3D Structure
ModBase 3D Structure for P41143
Immunogen
Synthetic peptide corresponding to the carboxyl terminal of the delta opioid receptor (carrier protein).

Product Categories/Family for anti-OPRD1 antibody

Antibodies; Abs to Opioid Receptors; Agonists
Applications Tested/Suitable for anti-OPRD1 antibody
Immunoprecipitation (IP)
Application Notes for anti-OPRD1 antibody
Suitable for use in Immunoprecipitation.
Dilution: Immunoprecipitation: 1:250-12000

Other Notes

Small volumes of anti-OPRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OPRD1 purchase

MBS629914 is an antibody targeting OPRD1. Also known as Opioid Receptor, delta, CT, aa360-372. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for OPRD1. It may not necessarily be applicable to this product.

NCBI GI #
119628077
NCBI GeneID
4985
UniProt Primary Accession #
P41143
UniProt Secondary Accession #
B5B0B8
UniProt Related Accession #
P41143
NCBI Official Full Name
opioid receptor, delta 1
NCBI Official Synonym Full Names
opioid receptor, delta 1
NCBI Official Symbol
OPRD1
NCBI Official Synonym Symbols
OPRD
UniProt Protein Name
Delta-type opioid receptor
Protein Family
Delta-type opioid receptor
UniProt Gene Name
OPRD1
UniProt Synonym Gene Names
OPRD
UniProt Entry Name
OPRD_HUMAN
NCBI Protein Information
delta-type opioid receptor; DOR-1; D-OR-1; OTTHUMP00000003778; delta opioid receptor 1

UniProt Comments for OPRD1

DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1p36.1-p34.3

Cellular Component: postsynaptic membrane; neuron projection; integral to plasma membrane; cytoplasm; plasma membrane; nerve terminal; intrinsic to plasma membrane; vesicle; lipid raft

Molecular Function: neuropeptide binding; protein binding; opioid receptor activity

Biological Process: adult locomotory behavior; activation of CREB transcription factor; regulation of calcium ion transport; sensory perception of pain; positive regulation of peptidyl-serine phosphorylation; negative regulation of protein oligomerization; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; G-protein coupled receptor protein signaling pathway; regulation of mitochondrial membrane potential; protein import into nucleus, translocation; neuropeptide signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; regulation of sensory perception of pain; G-protein signaling, adenylate cyclase inhibiting pathway
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Research Articles on OPRD1

1. data suggest that an increased constitutive internalization and/or concurrent signaling of the delta-opioid receptor-Cys27 variant affects APP processing through altered endocytic trafficking of APP

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OPRD1 antibody

 Reference Product  PubMed Publications
 OPRM1 antibody  >17 publications with OPRD1 and OPRM1
 OPRK1 antibody  >12 publications with OPRD1 and OPRK1
 GNAZ antibody  >1 publications with OPRD1 and GNAZ
 ARRB2 antibody  >1 publications with OPRD1 and ARRB2

Pathways associated with anti-OPRD1 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with anti-OPRD1 antibody

 Disease Name  Pubmed Publications
 Pain Antibodies  >9 publications with OPRD1 and Pain
 Autistic Disorder Antibodies  >1 publications with OPRD1 and Autistic Disorder
 Child Development Disorders, Pervasive Antibodies  >1 publications with OPRD1 and Child Development Disorders, Pervasive
 Anxiety Disorders Antibodies  >1 publications with OPRD1 and Anxiety Disorders
 Hepatitis Antibodies  >1 publications with OPRD1 and Hepatitis

Organs/Tissues associated with anti-OPRD1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with OPRD1 and Brain
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