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FAU Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS629945

This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has… More details

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Product Overview

Online Datasheet in PDF
Product Name
FAU, Polyclonal Antibody
Full Product Name
FAU, ID (Ubiquitin-like Protein FUBI)
Product Gene Name
anti-FAU antibody
Product Synonym Names
Anti -FAU, ID (Ubiquitin-like Protein FUBI)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human FAU.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
6,648 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (64888099..64889672, complement). Location: 11q13
OMIM
134690
3D Structure
ModBase 3D Structure for P62861
Immunogen
Synthetic peptide selected from the center region of human FUBI (KLH).

Product Categories/Family for anti-FAU antibody

Antibodies; Abs to Ubiquitin
Applications Tested/Suitable for anti-FAU antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-FAU antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:250-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-FAU antibody

Western blot analysis of anti-FUBI Center Pab (AP1600c) in Hela and T47D cell line lysates. FUBI Center(arrow) was detected using the purified Pab.
Rabbit Anti-FAU Polyclonal Antibody – Cat# MBS629945

Immunohistochemistry (IHC) of anti-FAU antibody

Formalin-fixed and paraffin-embedded human colon carcinoma reacted with FUBI Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-FAU Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS629945

Other Notes

Small volumes of anti-FAU antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FAU purchase

MBS629945 is an antibody targeting FAU. Also known as FAU, ID (Ubiquitin-like Protein FUBI). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FAU. It may not necessarily be applicable to this product.

NCBI GI #
31303
NCBI GeneID
2197
UniProt Primary Accession #
P62861
UniProt Secondary Accession #
Q05472; Q95261; Q9H5V4
UniProt Related Accession #
P35544; P62861; Q9P1M0
NCBI Official Full Name
fau
NCBI Official Synonym Full Names
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
NCBI Official Symbol
FAU
NCBI Official Synonym Symbols
S30; FAU1; Fub1; Fubi; asr1; RPS30; FLJ22986; MNSFbeta
UniProt Protein Name
40S ribosomal protein S30
Protein Family
40S ribosomal protein
UniProt Gene Name
FAU
UniProt Entry Name
RS30_HUMAN
NCBI Protein Information
ubiquitin-like protein fubi and ribosomal protein S30; OTTHUMP00000230421; OTTHUMP00000230422; OTTHUMP00000230423; OTTHUMP00000230424; OTTHUMP00000230425; OTTHUMP00000230427; 40S ribosomal protein S30; ubiquitin-like-S30 fusion protein; FAU-encoded ubiquitin-like protein; FBR-MuSV-associated ubiquitously expressed; monoclonal nonspecific suppressor factor beta; Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)

UniProt Comments for FAU

RPS30: This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin. [provided by RefSeq, Jul 2008]

Protein type: Ribosomal; Translation; Apoptosis

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: extracellular space; small ribosomal subunit; cytosol

Molecular Function: structural constituent of ribosome; RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; translation; viral reproduction; viral infectious cycle; translational termination; defense response to Gram-positive bacterium; translational elongation; cellular protein metabolic process; innate immune response in mucosa; mRNA catabolic process, nonsense-mediated decay; antibacterial humoral response; translational initiation; viral transcription; gene expression
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Research Articles on FAU

1. siRNA-mediated downregulation of either Fau or Bcl-G expression inhibited apoptosis, and the inhibition produced by combining the two siRNAs was consistent with control of Bcl-G by Fau.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-FAU antibody

 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytoplasmic Ribosomal Proteins Pathway antibodies  Cytoplasmic Ribosomal Proteins Pathway Diagram
 Diabetes Pathways antibodies  Diabetes Pathways Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Eukaryotic Translation Termination Pathway antibodies  Eukaryotic Translation Termination Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies  Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram

Organs/Tissues associated with anti-FAU antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >147 publications with FAU and Brain
 Blood Antibodies  >81 publications with FAU and Blood
 Liver Antibodies  >51 publications with FAU and Liver
 Muscle Antibodies  >33 publications with FAU and Muscle
 Heart Antibodies  >33 publications with FAU and Heart
 Nerve Antibodies  >28 publications with FAU and Nerve
 Eye Antibodies  >27 publications with FAU and Eye
 Bone Antibodies  >27 publications with FAU and Bone
 Vascular Antibodies  >19 publications with FAU and Vascular
 Kidney Antibodies  >16 publications with FAU and Kidney
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