• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CRAT Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS630058

CRAT is carnitine acetyltransferase (CRAT), which is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CRAT, Polyclonal Antibody
Full Product Name
CRAT, NT (Carnitine O-acetyltransferase, Carnitine Acetylase, Carnitine Acetyltransferase, CrAT, CAT, CAT1)
Product Gene Name
Product Synonym Names
Anti -CRAT, NT (Carnitine O-acetyltransferase, Carnitine Acetylase, Carnitine Acetyltransferase, CrAT, CAT, CAT1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human CRAT.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
70,858 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (131857073..131873070, complement). Location: 9q34.1
OMIM
600184
3D Structure
ModBase 3D Structure for P43155
Immunogen
Synthetic peptide selected from the N-terminal region of human CRAT (KLH).
Applications Tested/Suitable for anti-CRAT antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CRAT antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100

Western Blot (WB) of anti-CRAT antibody

Western blot analysis of CRAT antibody (N-term) in CEM cell line lysates (35ug/lane). CRAT (arrow) was detected using the purified Pab.
Rabbit Anti-CRAT Polyclonal Antibody – Cat# MBS630058

Immunohistochemistry (IHC) of anti-CRAT antibody

CRAT Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human Skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRAT Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-CRAT Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS630058

Other Notes

Small volumes of anti-CRAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRAT purchase

MBS630058 is an antibody targeting CRAT. Also known as CRAT, NT (Carnitine O-acetyltransferase, Carnitine Acetylase, Carnitine Acetyltransferase, CrAT, CAT, CAT1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CRAT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
carnitine O-acetyltransferase isoform 1
NCBI Official Synonym Full Names
carnitine O-acetyltransferase
NCBI Official Symbol
CRAT
NCBI Official Synonym Symbols
CAT1
UniProt Protein Name
Carnitine O-acetyltransferase
UniProt Synonym Protein Names
Carnitine acetyltransferase
UniProt Gene Name
CRAT
UniProt Synonym Gene Names
CAT1; Carnitine acetylase; CAT; CrAT
UniProt Entry Name
CACP_HUMAN
NCBI Protein Information
carnitine O-acetyltransferase; CAT; carnitine acetylase; carnitine acetyltransferase

NCBI Summary for CRAT

This gene encodes carnitine acetyltransferase (CRAT), which is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Show more

UniProt Comments for CRAT

CRAT: Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. Belongs to the carnitine/choline acetyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Acetyltransferase; EC 2.3.1.7

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: peroxisomal matrix; mitochondrion; endoplasmic reticulum; mitochondrial inner membrane; peroxisome

Molecular Function: carnitine O-acetyltransferase activity; receptor binding

Biological Process: carnitine metabolic process, CoA-linked; fatty acid beta-oxidation using acyl-CoA oxidase; transport; cellular lipid metabolic process
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CRAT antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000