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GAGE2B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6301023

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GAGE2B, Polyclonal Antibody
Full Product Name
GAGE2B, NT (GAGE2B, GAGE2, G antigen 2B/2C, Cancer/testis antigen 4.2, G antigen 2C) (MaxLight 550)
Product Gene Name
Product Synonym Names
GAGE2B; GAGE2; G antigen 2B/2C; Cancer/testis antigen 4.2; G antigen 2C
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
300595
3D Structure
ModBase 3D Structure for Q13066
Immunogen
GAGE2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GAGE2B.
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-GAGE2B antibody

Applications Tested/Suitable for anti-GAGE2B antibody
Western Blot (WB), FLISA
Application Notes for anti-GAGE2B antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-GAGE2B antibody

Sun, F., et al. Mol. Cancer Ther. 8(12):3191-3202(2009). Gjerstorff, M.F., et al. Tissue Antigens 71(3):187-192(2008). Ross, M.T., et al. Nature 434(7031):325-337(2005). De Backer, O., et al. Cancer Res. 59(13):3157-3165(1999). Scarcella, D.L., et al. Clin. Cancer Res. 5(2):335-341(1999).

Other Notes

Small volumes of anti-GAGE2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAGE2B purchase

MBS6301023 is an antibody targeting GAGE2B. Also known as GAGE2B, NT (GAGE2B, GAGE2, G antigen 2B/2C, Cancer/testis antigen 4.2, G antigen 2C) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GAGE2B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G antigen 2B/2C
NCBI Official Synonym Full Names
G antigen 2C
NCBI Official Symbol
GAGE2C
NCBI Official Synonym Symbols
CT4.2; GAGE2; GAGE-2; GAGE-2C
UniProt Protein Name
G antigen 2B/2C
UniProt Synonym Protein Names
Cancer/testis antigen 4.2; CT4.2; G antigen 2C
Protein Family
UniProt Gene Name
GAGE2B
UniProt Synonym Gene Names
GAGE2; GAGE-2B; GAGE-2C; CT4.2
UniProt Entry Name
GAG2B_HUMAN
NCBI Protein Information
G antigen 2B/2C

NCBI Summary for GAGE2B

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
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UniProt Comments for GAGE2B

GAGE2B/C: Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes. Belongs to the GAGE family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: Xp11.23

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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