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CDH19 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS630127

CDH7 is a type II classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II… More details

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Product Overview

Online Datasheet in PDF
Product Name
CDH7 (CDH19), Polyclonal Antibody
Full Product Name
CDH7, NT (CDH7L1, Cadherin-7)
Product Gene Name
Product Synonym Names
Anti -CDH7, NT (CDH7L1, Cadherin-7)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human CDH7.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
87,002 Da
Chromosome Location
Chromosome: 18; NC_000018.9 (64168320..64271375, complement). Location: 18q22.1
OMIM
603016
3D Structure
ModBase 3D Structure for Q9H159
Immunogen
Synthetic peptide selected from the N-term region of human CDH7 (KLH).

Product Categories/Family for anti-CDH19 antibody

Applications Tested/Suitable for anti-CDH19 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CDH19 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50

Western Blot (WB) of anti-CDH19 antibody

Western Blot analysis of K562 cell line lysates (35ug/lane) using MBS630127. CDH7(arrow) was detected using the purified Pab.
Rabbit Anti-CDH19 Polyclonal Antibody – Cat# MBS630127

Immunohistochemistry (IHC) of anti-CDH19 antibody

Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with MBS630127, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of MBS630127 for immunohistochemistry.
Rabbit Anti-CDH19 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS630127

Flow Cytometry (FC/FACS) of anti-CDH19 antibody

Flow cytometric analysis of NCI-H292 cells using MBS630127 (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-CDH19 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS630127

Other Notes

Small volumes of anti-CDH19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDH19 purchase

MBS630127 is an antibody targeting CDH19. Also known as CDH7, NT (CDH7L1, Cadherin-7). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CDH19. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cadherin-19 isoform 1 preproprotein
NCBI Official Synonym Full Names
cadherin 19, type 2
NCBI Official Symbol
CDH19
NCBI Official Synonym Symbols
CDH7; CDH7L2
UniProt Protein Name
Cadherin-19
Protein Family
UniProt Gene Name
CDH19
UniProt Synonym Gene Names
CDH7L2
UniProt Entry Name
CAD19_HUMAN
NCBI Protein Information
cadherin-19

NCBI Summary for CDH19

This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012]
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UniProt Comments for CDH19

CDH19: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 18q22.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: calcium ion binding

Biological Process: homophilic cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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